Search Result "pim-1 inhibition"


Research Article

Identification of Pim-1 Kinase Inhibitors by Pharmacophore Model, MolecularDocking-based Virtual Screening, and Biological Evaluation

Journal: Current Computer-Aided Drug Design
Volume: 18 Issue: 3 Year: 2022 Page: 240-246
Author(s):

New Potent and Selective Inhibitor of Pim-1/3 Protein Kinases Sensitizes Human Colon Carcinoma Cells to Doxorubicin

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 14 Issue: 9 Year: 2014 Page: 1228-1236
Author(s): Pascale Moreau,Lyubov G. Dezhenkova,Fabrice Anizon,Lionel Nauton,Vincent Thery,Shuguang Liang,Dmitry N. Kaluzhny,Alexander A. Shtil

Review Article

Signal Transduction through JAK-STAT and NF-κB Regulated Pim-1 Kinase: Novel Target for Anticancer Leads

Journal: Current Signal Transduction Therapy
Volume: 13 Issue: 2 Year: 2018 Page: 83-104
Author(s): Sisir Nandi,Mohd Salman,Ankita Sharma,Mohit Kumar

Research Article

New Mechanistic Insight on the PIM-1 Kinase Inhibitor AZD1208 Using Multidrug Resistant Human Erythroleukemia Cell Lines and Molecular Docking Simulations

Journal: Current Topics in Medicinal Chemistry
Volume: 19 Issue: 11 Year: 2019 Page: 914-926
Author(s): Maiara Bernardes Marques,Michael González-Durruthy,Bruna Félix da Silva Nornberg,Bruno Rodrigues Oliveira,Daniela Volcan Almeida,Ana Paula de Souza Votto,Luis Fernando Marins

Research Article

Heterocyclization of Thiophenes Derived from Estrone Followed by Cytotoxic, HTRF Kinase and Pim-1 Kinase Evaluations

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 18 Issue: 12 Year: 2018 Page: 1711-1728
Author(s): Mahmoud A. Abdelaziz Mahmoud,Rafat M. Mohareb,Meshari. A. Al-Sharif

Research Article

The Uses of Dimedone for the Synthesis of Thiophene, Thiazole and Annulated Derivatives with Antitumor, Pim-1 Kinase Inhibitions, PAINS Evaluations and Molecular Docking

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 21 Issue: 16 Year: 2021 Page: 2258-2277
Author(s): Wagnat W. Wardakhan,Amira M. Elmetwally,Abeer A. Mohamed,Rafat M. Mohareb

Research Article

New Approaches for the Synthesis of Heterocyclic Compounds Corporating Benzo[d]imidazole as Anticancer Agents, Tyrosine, Pim-1 Kinases Inhibitions and their PAINS Evaluations

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 21 Issue: 3 Year: 2021 Page: 327-342
Author(s): Rafat M. Mohareb,Yara R. Milad,Bahaa M. Mostafa,Reem A. El-Ansary

Research Article

Synthesis of Thiazole, Thiophene, Pyran and Pyridine Derivatives Derived from 3-phenyl-1H-pyrazol-5(4H)-one with Anti-proliferative, Tyrosine Kinase and PIM-1 Kinase Inhibitions

Journal: Letters in Drug Design & Discovery
Volume: 17 Issue: 4 Year: 2020 Page: 485-501
Author(s): Rafat Milad Mohareb,Ibram Refat Mikhail

Review Article

Abnormal Signal Transduction via Over-expression of Pim-1 Regulated Senescence, Cell Cycle, Apoptosis and Metastatic Invasion: Novel Anticancer Targets and Their Potent Inhibitors from Marine Sources

Journal: Current Signal Transduction Therapy
Volume: 15 Issue: 1 Year: 2020 Page: 3-11
Author(s): Ankita Sharma,Sisir Nandi

Research Article

Design, Synthesis, Molecular Docking, and Biological Studies of New HeterocyclicCompounds Derived from β-Diketones as Novel EGFR and Pim-1 InhibitorsEndowed with Antitumor Activity

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 22 Issue: 14 Year: 2022 Page: 2558-2576
Author(s): Rafat Milad Mohareb,Noha M. Asaad Bagato,Ibrahim Taha Radwan

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