Search Result "orthosteric ligands."


Allosteric Modulators for Adenosine Receptors: An Alternative to the Orthosteric Ligands

Journal: Current Topics in Medicinal Chemistry
Volume: 10 Issue: 1 Year: 2010 Page: 976-992
Author(s): C. La Motta, S. Sartini, M. Morelli, S. Taliani, F. Da Settimo

Review Article

Insights into the Structural Aspects of the mGlu Receptor Orthosteric Binding Site

Journal: Current Topics in Medicinal Chemistry
Volume: 19 Issue: 2 Year: 2019 Page: 2421-2446
Author(s): Junliang Hao,Qi Chen

The Therapeutic Potential of Allosteric Ligands for Free Fatty Acid Sensitive GPCRs

Journal: Current Topics in Medicinal Chemistry
Volume: 13 Issue: 1 Year: 2013 Page: 14-25
Author(s): Brian D. Hudson, Trond Ulven, Graeme Milligan

Research Article

In Silico Identification of Novel Orthosteric Inhibitors of Sphingosine Kinase 1 (SK1)

Journal: Current Protein & Peptide Science
Volume: 19 Issue: 5 Year: 2018 Page: 430-444
Author(s): Ozge Bayraktar,Elif Ozkirimli,Kutlu O. Ulgen

The Different Ways through Which Specificity Works in Orthosteric and Allosteric Drugs

Journal: Current Pharmaceutical Design
Volume: 18 Issue: 9 Year: 2012 Page: 1311-1316
Author(s): Ruth Nussinov, Chung-Jung Tsai

Medicinal Chemistry of P2X Receptors: Agonists and Orthosteric Antagonists

Journal: Current Medicinal Chemistry
Volume: 22 Issue: 7 Year: 2015 Page: 915-928
Author(s): Catia Lambertucci,Diego Dal Ben,Michela Buccioni,Gabriella Marucci,Ajiroghene Thomas,Rosaria Volpini

Review Article

Advances in Dopamine D1 Receptor Ligands for Neurotherapeutics

Journal: Current Topics in Medicinal Chemistry
Volume: 19 Issue: 16 Year: 2019 Page: 1365-1380
Author(s): Daniel E. Felsing,Manish K. Jain,John A. Allen

Druggable Orthosteric and Allosteric Hot Spots to Target Protein-protein Interactions

Journal: Current Pharmaceutical Design
Volume: 20 Issue: 8 Year: 2014 Page: 1293-1301
Author(s): Buyong Ma, Ruth Nussinov

Review Article

Molecular Basis of Modulating Adenosine Receptors Activities

Journal: Current Pharmaceutical Design
Volume: 25 Issue: 7 Year: 2019 Page: 817-831
Author(s): Mohammed Nooraldeen Mahmod Al-Qattan,Mohd Nizam Mordi

A Hydrazide Linker Strategy for Heterobivalent Compounds as Ortho- and Allosteric Ligands of Acetylcholine-Binding Proteins

Journal: Current Topics in Medicinal Chemistry
Volume: 11 Issue: 2 Year: 2011 Page: 2731-2748
Author(s): Paul W. Elsinghorst, Wolfgang Hartig, Daniela Gundisch, Klaus Mohr, Christian Trankle, Michael Gutschow

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