Search Result "novel leads"


Lead Generation - Enhancing the Success of Drug Discovery by Investing in the Hit to Lead Process

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 6 Issue: 1 Year: 2003 Page: 51-66
Author(s): Alexander Alanine, Matthias Nettekoven, Edward Roberts, Andrew W. Thomas

Novel, Acidic CCR2 Receptor Antagonists: Lead Optimization

Journal: Letters in Drug Design & Discovery
Volume: 4 Issue: 4 Year: 2007 Page: 263-271
Author(s): O. A. Dasse, J. L. Evans, H.-X. Zhai, D. Zou, J. T. Kintigh, F. Chan, K. Hamilton, E. Hill, J. B. Eckman, P. J. Higgins, A. Volosov, P. Collart, J.-M. Nicolas, R.K. Kondru, C.E. Schwartz

Applications of Biophysical Tools to Target-Based Discovery of Novel Antibacterial Leads

Journal: Current Drug Targets
Volume: 13 Issue: 3 Year: 2012 Page: 388-408
Author(s): Sushmita Lahiri, Steven Kazmirski, Gunther Kern, Gautam Sanyal

Discovery of Novel CK2 Leads by Cross-Docking Based Virtual Screening

Journal: Medicinal Chemistry
Volume: 10 Issue: 6 Year: 2014 Page: 628-639
Author(s): Haopeng Sun, Xiaowen Wu, Xiaoli Xu, Zhengyu Jiang, Zongliang Liu, Qidong You

Knowledge-Driven Lead Discovery

Journal: Mini-Reviews in Medicinal Chemistry
Volume: 5 Issue: 1 Year: 2005 Page: 1045-1052
Author(s): Bernard Pirard

Efficient Identification of Novel Leads by Dynamic Focused Screening: PDK1 Case Study

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 13 Issue: 1 Year: 2010 Page: 16-26
Author(s): Dongyu Sun, Joon Jung, Thomas S. Rush III, Zangwei Xu, Michael J. Weber, Ekaterina Bobkova, Alan Northrup, Ilona Kariv

New Lead Structures in Antifungal Drug Discovery

Journal: Current Medicinal Chemistry
Volume: 18 Issue: 5 Year: 2011 Page: 733-766
Author(s): Chunquan Sheng, Wannian Zhang

Fragment-based Designing for the Generation of Novel Leads Against BACE1

Journal: Central Nervous System Agents in Medicinal Chemistry
Volume: 15 Issue: 1 Year: 2015 Page: 52-64
Author(s): Sucharita Das,Sandipan Chakraborty,Soumalee Basu

Review Article

Prospective Plant Based Anticancer Lead Molecules

Journal: Current Topics in Medicinal Chemistry
Volume: 18 Issue: 30 Year: 2018 Page: 2567-2583
Author(s): Prabhjot Kaur,Vikas Sharma

Fluorescent Probes for Detection of Lead Ion

Journal: Recent Innovations in Chemical Engineering
Volume: 7 Issue: 1 Year: 2014 Page: 10-16
Author(s): Tan-cheng Zheng,Fan-yong Yan,De-chao Shi,Yu Zou,Sheng-lan Zhang,Li Chen

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