Search Result "non-renal clearance"


Predicting Clearance in Humans from In Vitro Data

Journal: Current Topics in Medicinal Chemistry
Volume: 11 Issue: 4 Year: 2011 Page: 334-339
Author(s): R. Scott Obach

A Novel Plated Hepatocyte Relay Assay (PHRA) for In Vitro Evaluation of Hepatic Metabolic Clearance of Slowly Metabolized Compounds

Journal: Drug Metabolism Letters
Volume: 10 Issue: 1 Year: 2016 Page: 3-15
Author(s): Chi-Chi Peng,Utkarsh Doshi,Chandra Prakash,Albert P. Li

Covariates of Amikacin Clearance in Neonates: The Impact of Postnatal Age on Predictability

Journal: Drug Metabolism Letters
Volume: 2 Issue: 4 Year: 2008 Page: 286-289
Author(s): Karel Allegaert, Isabelle Scheers, Veerle Cossey, Brian J. Anderson

ARC - Augmented Renal Clearance

Journal: Current Pharmaceutical Biotechnology
Volume: 12 Issue: 1 Year: 2011 Page: 2020-2029
Author(s): Andrew A. Udy, Michael T. Putt, Robert J. Boots, Jeffrey Lipman

Research Article

The Role of Aldehyde Oxidase in the Metabolic Clearance of Substituted Benzothiazoles

Journal: Drug Metabolism Letters
Volume: 14 Issue: 2 Year: 2021 Page: 126-136
Author(s): Yohannes Teffera,Jingzhou Liu,Paul Krolikowski,Zhiyang Zhao

Controversies in Allometric Scaling for Predicting Human Drug Clearance: An Historical Problem and Reflections on What Works and What Does Not

Journal: Current Topics in Medicinal Chemistry
Volume: 11 Issue: 4 Year: 2011 Page: 340-350
Author(s): Huadong Tang, Michael Mayersohn

Systematic and Pairwise Analysis of the Effects of Aromatic Halogenation and Trifluoromethyl Substitution on Human Liver Microsomal Clearance

Journal: Drug Metabolism Letters
Volume: 5 Issue: 4 Year: 2011 Page: 232-242
Author(s): Hao Sun, Christopher E. Keefer, Dennis O. Scott

Rate-Determining and Rate-Limiting Steps in the Clearance and Excretion of a Potent and Selective p21-Activated Kinase Inhibitor: A Case Study of Rapid Hepatic Uptake and Slow Elimination in Rat

Journal: Drug Metabolism Letters
Volume: 10 Issue: 2 Year: 2016 Page: 91-100
Author(s): Peter W. Fan, Jacob Z. Chen, M. Allan Jaochico, Hank La, Ning Liu, Teresa Mulder, Robert T. Cass, Matthew Durk, Kirsten Messick, Nicole Valle, Shannon Liu, Wendy Lee, James J. Crawford, Joachim Rudolf, Lesley J. Murray, S. Cyrus Khojasteh, Matthew Wright

Review Article

Metabolic Enzyme System and Transport Pathways in Chronic Kidney Diseases

Journal: Current Drug Metabolism
Volume: 19 Issue: 7 Year: 2018 Page: 568-576
Author(s): Bin Liu,Fangmei Luo,Xiuju Luo,Shaobin Duan,Zhicheng Gong,Jie Peng

How to Measure Renal Function in Children - What is the Role of Cystatin C?

Journal: Current Pediatric Reviews
Volume: 2 Issue: 3 Year: 2006 Page: 225-231
Author(s): Guido Filler

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