Search Result "non-quaternary oximes"


Research Article

In vitro and in silico Evaluation of Non-Quaternary Reactivators of AChE as Antidotes of Organophosphorus Poisoning - a New Hope or a Blind Alley?

Journal: Medicinal Chemistry
Volume: 14 Issue: 3 Year: 2018 Page: 281-292
Author(s): Ondrej Soukup,Jan Korabecny,David Malinak,Eugenie Nepovimova,Ngoc L. Pham,Kamil Musilek,Martina Hrabinova,Vendula Hepnarova,Rafael Dolezal,Petr Pavek,Petr Jost,Tereza Kobrlova,Jana Jankockova,Lukas Gorecki,Miroslav Psotka,Thuy D. Nguyen,Karl Box,Breeze Outhwaite,Martina Ceckova,Ales Sorf,Daniel Jun,Kamil Kuca

Kinetic Analysis of Oxime Interactions with Acetylcholinesterase as a Basis for the Evaluation of Oxime Efficacy in Organophosphate Poisoning

Journal: Current Bioactive Compounds
Volume: 6 Issue: 1 Year: 2010 Page: 16-22
Author(s): F. Worek, P. Eyer, N. Aurbek, H. Thiermann

Entry of Oximes into the Brain: A Review

Journal: Current Medicinal Chemistry
Volume: 15 Issue: 8 Year: 2008 Page: 743-753
Author(s): D. E. Lorke, H. Kalasz, G. A. Petroianu, K. Tekes

An In Silico Stereo-electronic Comparison of Conventional Pyridinium Oximes and K-oximes for Organophosphate (OP) Poisoning

Journal: Medicinal Chemistry
Volume: 8 Issue: 2 Year: 2012 Page: 230-245
Author(s): Apurba K. Bhattacharjee, Kamil Kuca, Kamil Musilek, Richard K. Gordon

Current Study on the Development of Bis-pyridinium Oxime Reactivators for the Antidotal Treatment of Poisoning by Toxic Organophosphorus Agents

Journal: Current Organic Chemistry
Volume: 15 Issue: 3 Year: 2011 Page: 433-444
Author(s): Young-Sik Jung, Kamil Kuca

The Development of New Structural Analogues of Oximes for the Antidotal Treatment of Poisoning by Nerve Agents and the Comparison of Their Reactivating and Therapeutic Efficacy with Currently Available Oximes

Journal: Current Organic Chemistry
Volume: 11 Issue: 3 Year: 2007 Page: 267-283
Author(s): Jiri Kassa, Kamil Kuca, Lucie Bartosova, Gabriela Kunesova

Progress on the Development of Oxime Derivatives as a Potential Antidote for Organophosphorus Poisoning

Ebook: Frontiers in Clinical Drug Research - CNS and Neurological Disorders
Volume: 12 Year: 2024
Author(s):
Doi: 10.2174/9789815179842124120008

Pyridinium Oxime Reactivators of Cholinesterase Inhibited by Diisopropyl- Fluorophosphate (DFP): Predictive Value of In-Vitro Testing for In-Vivo Efficacy

Journal: Mini-Reviews in Medicinal Chemistry
Volume: 8 Issue: 1 Year: 2008 Page: 1328-1342
Author(s): G. A. Petroianu, D. E. Lorke

Structure-Activity Relationship and Efficacy of Pyridinium Oximes in the Treatment of Poisoning with Organophosphorus Compounds: A Review of Recent Data

Journal: Current Topics in Medicinal Chemistry
Volume: 12 Issue: 16 Year: 2012 Page: 1775-1789
Author(s): Milan Jokanovic

Research Article

Oxime K033-Reactivation Activity of Cholinesterases Inhibited by Various Nerve Agents and Organophosphorus Pesticides

Journal: Letters in Drug Design & Discovery
Volume: 15 Issue: 11 Year: 2018 Page: 1124-1130
Author(s): Kamil Kuca,Kamil Musilek,Daniel Jun,Jaroslav Pejchal,Ondrej Krejcar,Marek Penhaker,Qinghua Wu,Raquel O. Lopes,Teodorico C. Ramalho,Tanos C.C. Franca,Eugenie Nepovimova,Ondrej Soukup

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