Search Result "molecular simplification"


Research Article

Benzodiazepine Scaffold as Drug-like Molecular Simplification of FR235222: A Chemical Tool for Exploring HDAC Inhibition

Journal: Current Topics in Medicinal Chemistry
Volume: 17 Issue: 4 Year: 2017 Page: 441-459
Author(s): Maurizio Taddei,Manuela Rodriquez,Antonello Petrella,Caterina Fattorusso,Luca Rastrelli,Eduardo Sobarzo-Sánchez,Ettore Novellino,Anna Maria D`Ursi,Mario Scrima,Manuela Grimaldi,Marco Persico,Valentina Bizzarro,Elena Cini,Ilaria Moronese,Rosario Randino

Design of New Drugs for the Treatment of Alzheimer’s Disease Based on Tacrine Structure

Journal: Current Drug Targets
Volume: 14 Issue: 3 Year: 2013 Page: 378-397
Author(s): Roney A.N. de Aquino,Luzia V. Modolo,Rosemeire B. Alves,Angelo de Fatima

Molecular Electrostatic Potential as a Graph

Journal: Current Computer-Aided Drug Design
Volume: 9 Issue: 2 Year: 2013 Page: 272-280
Author(s): Edgar E. Daza,Julio Maza,Raul Torres

Research Article

Aryl-isoquinoline as a Potential Scaffold for Novel Antitumor Agentsagainst Glioblastoma Cells

Journal: Letters in Drug Design & Discovery
Volume: 21 Issue: 5 Year: 2024 Page: 948-960
Author(s): Thais Batista Fernandes,Glaucio Monteiro Ferreira,Priscila Oliveira de Souza,Vitor Galvão Lopes,Mônica Franco Zannini Junqueira Toledo,Gabriela Nogueira Debom,Sandra Valeria Vassiliades,Neuza Mariko Aymoto Hassimotto,Mario Hiroyuki Hirata

Molecular Dynamics Simulation in RNA Interference

Journal: Current Medicinal Chemistry
Volume: 21 Issue: 17 Year: 2014 Page: 1968-1975
Author(s): Xia Wang,Yonghua Wang,Lei Zheng,Jianxin Chen

Multiscale Molecular Dynamics of Protein Aggregation

Journal: Current Protein & Peptide Science
Volume: 12 Issue: 3 Year: 2011 Page: 221-234
Author(s): Cesar L. Avila, Nils J. D. Drechsel, Raul Alcantara, Jordi Villa-Freixa

Review Article

Translating Nucleic Acid Amplification Assays to the Microscale: Lab on a Chip for Point-of-Care Molecular Diagnostics

Journal: Current Analytical Chemistry
Volume: 12 Issue: 5 Year: 2016 Page: 386-396
Author(s): Michael G. Mauk,Jinzhao Song,Yubing Tong,Haim H. Bau,Changchun Liu

Review Article

Matrine-Family Alkaloids: Versatile Precursors for Bioactive Modifications

Journal: Medicinal Chemistry
Volume: 16 Issue: 4 Year: 2020 Page: 431-453
Author(s): Xiao-hua Cai,Hong-yan Zhang,Bing Xie

Molecular Docking: A Powerful Approach for Structure-Based Drug Discovery

Journal: Current Computer-Aided Drug Design
Volume: 7 Issue: 2 Year: 2011 Page: 146-157
Author(s): Xuan-Yu Meng, Hong-Xing Zhang, Mihaly Mezei, Meng Cui

Synthesis, Separation, and Molecular Structures of Endohedral Fullerenes

Journal: Current Organic Chemistry
Volume: 16 Issue: 9 Year: 2012 Page: 1079-1094
Author(s): Shangfeng Yang

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