Search Result "maximum tolerated dose (MTD)"


A New Model for Determining the MTD During Phase-I Trials in Pediatric Oncology

Journal: Current Topics in Medicinal Chemistry
Volume: 12 Issue: 15 Year: 2012 Page: 1660-1664
Author(s): C. Faivre,D. Barbolosi,A. Iliadis

Impaired Autophagy Mediates Resistance to Low-Dose Metronomic Cyclophosphamide Chemotherapy

Journal: Clinical Cancer Drugs
Volume: 1 Issue: 2 Year: 2014 Page: 116-126
Author(s): Annabelle Chow,Giulio Francia,Andrew Kouri,Christina Lee,John M. Ebos,Robert S. Kerbel,Urban Emmenegger

Clinical Trial open access plus

A Phase I Study of OMN54 (Aneustat™) in Patients with Advanced Malignancies

Journal: Clinical Cancer Drugs
Volume: 7 Issue: 2 Year: 2020 Page: 125-132
Author(s): Karen A. Gelmon,Christian Kollmannsberger,Stephen Chia,Anna V. Tinker,Teresa Mitchell,Stephen Lam,Teresa Joshi,David Kwok,John Ostrem,Simon Sutcliffe,Daniel J. Renouf

Assessment of the Health Effects of Chemicals in Humans: I. QSAR Estimation of the Maximum Recommended Therapeutic Dose (MRTD) and No Effect Level (NOEL) of Organic Chemicals Based on Clinical Trial Data1

Journal: Current Drug Discovery Technologies
Volume: 1 Issue: 1 Year: 2004 Page: 61-76
Author(s): Edwin J. Matthews, Naomi L. Kruhlak, R. Daniel Benz, Joseph F. Contrera

Cellular and Molecular Surrogate Markers to Monitor Targeted and Non- Targeted Antiangiogenic Drug Activity and Determine Optimal Biologic Dose

Journal: Current Cancer Drug Targets
Volume: 5 Issue: 7 Year: 2005 Page: 551-559
Author(s): Yuval Shaked, Guido Bocci, Raquel Munoz, Shan Man, John M.L. Ebos, Daniel J. Hicklin, Francesco Bertolini, Robert DAmato, Robert S. Kerbel

Research Article

Cholinesterase Inhibitor 6-Chlorotacrine - In Vivo Toxicological Profile and Behavioural Effects

Journal: Current Alzheimer Research
Volume: 15 Issue: 6 Year: 2018 Page: 552-560
Author(s): Jan Misik,Eugenie Nepovimova,Jaroslav Pejchal,Jiri Kassa,Jan Korabecny,Ondrej Soukup

Anticholinesterase and Pharmacokinetic Profile of Phenserine in Healthy Elderly Human Subjects

Journal: Current Alzheimer Research
Volume: 2 Issue: 4 Year: 2005 Page: 483-492
Author(s): Nigel H. Greig, Jon Ruckle, Patrick Comer, Lidia Brownell, Harold W. Holloway, Douglas R. Flanagan Jr., Craig J. Canfield, Robert G. Burford

Efficacy and Toxicological Studies of Cremophor EL Free Alternative Paclitaxel Formulation

Journal: Current Drug Safety
Volume: 6 Issue: 5 Year: 2011 Page: 329-338
Author(s): Puneet Utreja, Subheet Jain, Subodh Yadav, K. L. Khandhuja, A. K. Tiwary

Lipid-Based Nanoparticulate Systems for the Delivery of Anti-Cancer Drug Cocktails: Implications on Pharmacokinetics and Drug Toxicities

Journal: Current Drug Metabolism
Volume: 10 Issue: 8 Year: 2009 Page: 861-874
Author(s): Gigi N.C. Chiu, Man-Yi Wong, Leong-Uung Ling, Ishaque M. Shaikh, Kuan-Boone Tan, Anumita Chaudhury, Bee-Jen Tan

Journal: Current Pharmaceutical Biotechnology
Volume: 2 Issue: 4 Year: 2001 Page: 341-349
Author(s): C. Krasner, R.M. Joyce

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