Search Result "leadoptimization"


Review Article

Recent Advances in Structural Modification Strategies for LeadOptimization of Tyrosine Kinase Inhibitors to Explore NovelAnticancer Agents

Journal: Current Medicinal Chemistry
Volume: 30 Issue: 24 Year: 2023 Page: 2734-2761
Author(s):

ADME Optimization and Toxicity Assessment in Drug Discovery

Ebook: Frontiers in Medicinal Chemistry
Volume: 8 Year: 2016
Author(s): Gary W. Caldwell
Doi: 10.2174/9781681081755116080003

PfDHFR Enzyme Inhibitors: Rational Design Using Pharmacoinformatic Tools

Ebook: Frontiers in Medicinal Chemistry
Volume: 7 Year: 2015
Author(s): Sheenu Abbat,Shweta Bhagat,Prasad V. Bharatam
Doi: 10.2174/9781608059706115070009

Research Article

Synthesis, In vitro, and Docking Analysis of C-3 Substituted Coumarin Analogues as Anticancer Agents

Journal: Current Computer-Aided Drug Design
Volume: 17 Issue: 2 Year: 2021 Page: 161-172
Author(s): Anuradha Thakur,Kamalpreet Kaur,Praveen Sharma,Ramit Singla,Sandeep Singh,Vikas Jaitak

Dynamics of Biomolecular Ligand Recognition

Ebook: Computational Modeling and Simulation in Biomedical Research
Volume: 1 Year: 2024
Author(s):
Doi: 10.2174/9789815165463124010008

Review Article

PBPK Modeling - A Predictive, Eco-Friendly, Bio-Waiver Tool for Drug Research

Journal: Current Drug Discovery Technologies
Volume: 14 Issue: 3 Year: 2017 Page: 142-155
Author(s): Baishakhi De,Koushik Bhandari,Ranjan Mukherjee,Prakash Katakam,Shanta K. Adiki,Rohit Gundamaraju,Analava Mitra

Recent Trends of Modern Mass Spectrometry: Application towards Drug Discovery and Development Process

Ebook: Applications of Modern Mass Spectrometry
Volume: 2 Year: 2024
Author(s):
Doi: 10.2174/9789815050059124020008

Targeting the Eph-ephrin System with Protein-Protein Interaction (PPI) Inhibitors

Journal: Current Drug Targets
Volume: 16 Issue: 10 Year: 2015 Page: 1048-1056
Author(s): Massimiliano Tognolini,Alessio Lodola

Strategy of Utilizing In Vitro and In Vivo ADME Tools for Lead Optimization and Drug Candidate Selection

Journal: Current Topics in Medicinal Chemistry
Volume: 5 Issue: 1 Year: 2005 Page: 1033-1038
Author(s): Suresh K. Balani, Gerald T. Miwa, Liang-Shang Gan, Jing-Tao Wu, Frank W. Lee

Preface

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 3 Issue: 6 Year: 2000 Page: ii-ii
Author(s): Grzegorz Bazylak

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