Search Result "isosteric substituent"
Isosteric and Spatial Considerations of Drugs
Ebook: Medicinal Chemistry for Pharmacy Students
Volume: 1 Year: 2018
Author(s): M. O. Faruk Khan,Timothy J. Hubin
Doi: 10.2174/9781681086873118010008
Targeting Enzymes with Phosphonate-Based Inhibitors: Mimics of Tetrahedral Transition States and Stable Isosteric Analogues of Phosphates
Journal: Current Enzyme Inhibition
Volume: 2 Issue: 1 Year: 2006 Page: 61-72
Author(s): L. Azema, R. Baron, S. Ladame
Design, Synthesis and Docking Studies of Hydroxyethylamine and Hydroxyethylsulfide BACE-1 Inhibitors
Journal: Protein & Peptide Letters
Volume: 16 Issue: 1 Year: 2009 Page: 86-90
Author(s): Luca Rizzi, Nadia Vaiana, Francesca Sagui, Eva Genesio, Elena Pilli, Valentina Porcari, Sergio Romeo
Biphenyl Amides and Isosteres as MCH R1 Antagonists
Journal: Current Topics in Medicinal Chemistry
Volume: 7 Issue: 1 Year: 2007 Page: 1455-1470
Author(s): Donald L. Hertzog, David R. Witty
A Review of Cationic Arylfurans and Their Isosteres: Synthesis and Biological Importance
Journal: Current Organic Chemistry
Volume: 23 Issue: 24 Year: 2019 Page: 2751-2782
Author(s): Mohamed A. Ismail,Wael M. El-Sayed,Saad Shaaban,Ghada A. Abdelwahab,Wafaa S. Hamama
Design and Synthesis of Novel Diaryl Heterocyclic Derivatives as Selective Cyclooxygenase-2
Journal: Letters in Drug Design & Discovery
Volume: 5 Issue: 2 Year: 2008 Page: 127-133
Author(s): S. X. Li, X. D. Deng, F. L. Jiang, Y. J. Zhao, W. S. Xiao, X. Z. Kuang, X. M. Sun
The Influence of Substituents on the Hydroxyl-Bearing Carbon in the Aza-Payne Rearrangement of Aziridinemethanols
Journal: Letters in Organic Chemistry
Volume: 6 Issue: 5 Year: 2009 Page: 412-415
Author(s): Wenjin Xu, Jun Zhang, Hao Guo, Qifeng Zhu, Xianming Hu
Solution Phase Synthesis of a 3,5,7-Substituted Indolin-2-one Library as Potential CDK2 Inhibitor Isosteres
Journal: Letters in Drug Design & Discovery
Volume: 5 Issue: 1 Year: 2008 Page: 43-47
Author(s): Dmytro O. Tymoshenko, Brian T. Gregg, Matthew J. Hirsch, Jennifer L. Butcher
Recent Progress in the Medicinal Chemistry of γ-Secretase Inhibitors
Journal: Current Topics in Medicinal Chemistry
Volume: 8 Issue: 1 Year: 2008 Page: 17-33
Author(s): Richard E. Olson, Charles F. Albright
Studies of Benzothiadiazine Derivatives as Hepatitis C Virus NS5B Polymerase Inhibitors Using 3D-QSAR, Molecular Docking and Molecular Dynamics
Journal: Current Medicinal Chemistry
Volume: 17 Issue: 2 Year: 2010 Page: 2788-2803
Author(s): X. Wang, W. Yang, X. Xu, H. Zhang, Y. Li, Y. Wang