Search Result "intrinsic clearance"


Predicting Clearance in Humans from In Vitro Data

Journal: Current Topics in Medicinal Chemistry
Volume: 11 Issue: 4 Year: 2011 Page: 334-339
Author(s): R. Scott Obach

Prediction of Human Hepatic Clearance Using an In Vitro Plated Hepatocyte Clearance Model

Journal: Drug Metabolism Letters
Volume: 3 Issue: 4 Year: 2009 Page: 296-307
Author(s): Piyun Chao, Jeffrey Barminko, Eric Novik, Yi Han, Timothy Maguire, K.-C. Cheng

A High Throughput, 384-Well, Semi-Automated, Hepatocyte Intrinsic Clearance Assay for Screening New Molecular Entities in Drug Discovery

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 18 Issue: 5 Year: 2015 Page: 442-452
Author(s): Lance Heinle,Vincent Peterkin,Sonia M. de Morais,Gary J. Jenkins,Ilaria Badagnani

A Non-acidic Sulfaphenazole Analog Demonstrating High Intrinsic Clearance and Selectivity by Canine CYP2C21

Journal: Drug Metabolism Letters
Volume: 5 Issue: 4 Year: 2011 Page: 253-258
Author(s): Charles W. Locuson, Josh F. Alfaro, Matthew J. Zaya, Denis Billen, Julie A. White, Jeffrey P. Jones

Scaling In Vivo Pharmacokinetics from In Vitro Metabolic Stability Data in Drug Discovery

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 13 Issue: 2 Year: 2010 Page: 159-169
Author(s): Wendy Klopf, Philip Worboys

Apoptotic Cell Clearance and Autoimmune Disorder

Journal: Current Medicinal Chemistry
Volume: 14 Issue: 2 Year: 2007 Page: 2892-2897
Author(s): Masato Tanaka, Yasunobu Miyake

Calculating the Metabolic Clearance of a Mother Substance from the Clearance of its Analogue Tracer Measured by PET

Ebook: Functional Molecular Imaging In Hepatology
Volume: 1 Year: 2012
Author(s): Ludvik Bass,Michael Sørensen,Ole Lajord Munk,Susanne Keiding
Doi: 10.2174/978160805290511201010032

Impact of Input Parameters on the Prediction of Hepatic Plasma Clearance Using the Well-Stirred Model

Journal: Current Drug Metabolism
Volume: 11 Issue: 7 Year: 2010 Page: 583-594
Author(s): Hong Wan, Peter Bold, Lars-Olof Larsson, Johan Ulander, Sheila Peters, Boel Lofberg, Anna-Lena Ungell, Mats Nagard, Antonio Llinas

Atypical Enzyme Kinetics: Their Effect on In Vitro-In Vivo Pharmacokinetic Predictions and Drug Interactions

Journal: Current Drug Metabolism
Volume: 4 Issue: 5 Year: 2003 Page: 341-346
Author(s): Timothy S. Tracy

Review Article

Convection-Enhanced Delivery for Diffuse Intrinsic Pontine Glioma Treatment

Journal: Current Neuropharmacology
Volume: 15 Issue: 1 Year: 2017 Page: 116-128
Author(s): Zhiping Zhou, Ranjodh Singh, Mark M. Souweidane

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