Search Result "intramembrane proteolytic cleavage"


Proteolytic Cleavage of Notch: “HIT and RUN”

Journal: Current Molecular Medicine
Volume: 11 Issue: 4 Year: 2011 Page: 255-269
Author(s): G. van Tetering, M. Vooijs

Structural and Functional Determinants of γ-Secretase, an Intramembrane Protease Implicated in Alzheimers Disease

Journal: Current Genomics
Volume: 8 Issue: 8 Year: 2007 Page: 531-549
Author(s): Patrick C. Fraering

η-Secretase: Reduction of Amyloid Precursor Protein η-Site Cleavage in Alzheimers Disease

Journal: Current Alzheimer Research
Volume: 5 Issue: 2 Year: 2008 Page: 165-171
Author(s): Fuyuki Kametani

Alpha-Secretase Cleavage of the Amyloid Precursor Protein: Proteolysis Regulated by Signaling Pathways and Protein Trafficking

Journal: Current Alzheimer Research
Volume: 9 Issue: 2 Year: 2012 Page: 165-177
Author(s): Stefan F. Lichtenthaler

AICD Nuclear Signaling and Its Possible Contribution to Alzheimers Disease

Journal: Current Alzheimer Research
Volume: 9 Issue: 2 Year: 2012 Page: 200-216
Author(s): Uwe Konietzko

The Catalytic Core of γ-Secretase: Presenilin Revisited

Journal: Current Alzheimer Research
Volume: 5 Issue: 2 Year: 2008 Page: 147-157
Author(s): Harald Steiner

A Novel Immunotherapy for Alzheimers Disease: Antibodies against the β-Secretase Cleavage Site of APP

Journal: Current Alzheimer Research
Volume: 4 Issue: 4 Year: 2007 Page: 437-445
Author(s): Michal Arbel, Beka Solomon

ADAM17 as a Therapeutic Target in Multiple Diseases

Journal: Current Pharmaceutical Design
Volume: 15 Issue: 2 Year: 2009 Page: 2319-2335
Author(s): Joaquin Arribas, Cary Esselens

Presenilin and γ -Secretase Activity: A Viable Therapeutic Target for Alzheimers Disease?

Journal: Current Signal Transduction Therapy
Volume: 5 Issue: 2 Year: 2010 Page: 128-140
Author(s): Run Yan, Justin V. McCarthy

Similar Mechanisms Regulated by γ-Secretase are Involved in Both Directions of the Bi-Directional Notch-Delta Signaling Pathway as well as Play a Potential Role in Signaling Events Involving Type 1 Transmembrane Proteins

Journal: Current Stem Cell Research & Therapy
Volume: 3 Issue: 4 Year: 2008 Page: 288-302
Author(s): Kohzo Nakayama, Hisashi Nagase, Masahiro Hiratochi, Chang-Sung Koh, Takeshi Ohkawara

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