Search Result "hit-to-lead"
Lead Generation - Enhancing the Success of Drug Discovery by Investing in the Hit to Lead Process
Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 6 Issue: 1 Year: 2003 Page: 51-66
Author(s): Alexander Alanine, Matthias Nettekoven, Edward Roberts, Andrew W. Thomas
Trends in Hit-to-Lead: An Update
Ebook: Frontiers in Medicinal Chemistry
Volume: 3 Year: 2006
Author(s):
Doi: 10.2174/978160805206610603010653
Novel, Acidic CCR2 Receptor Antagonists: From Hit to Lead
Journal: Letters in Drug Design & Discovery
Volume: 4 Issue: 3 Year: 2007 Page: 185-191
Author(s): D. Zou, H.-X. Zhai, J. Eckman, P. Higgins, M. Gillard, L. Knerr, S. Carre, P. Pasau, P. Collart, J. Grassi
A Collaborative Hit-to-Lead Investigation Leveraging Medicinal Chemistry Expertise with High Throughput Library Design, Synthesis and Purification Capabilities
Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 9 Issue: 2 Year: 2006 Page: 123-130
Author(s): X. Yang, D. Parker, L. Whitehead, N. S. Ryder, B. Weidmann, M. Stabile-Harris, D. Kizer, M. McKinnon, A. Smellie, D. Powers
The Inhibition of Extended Spectrum β-Lactamases: Hits and Leads
Journal: Current Medicinal Chemistry
Volume: 21 Issue: 12 Year: 2014 Page: 1405-1434
Author(s): Davide Farina,Francesca Spyrakis,Alberto Venturelli,Simon Cross,Donatella Tondi,Maria Paola Costi
Nature-Derived Hit, Lead, and Drug-Like Small Molecules: Current Statusand Future Aspects Against Key Target Proteins of Coronaviruses
Journal: Mini-Reviews in Medicinal Chemistry
Volume: 22 Issue: 3 Year: 2022 Page: 498-549
Author(s): Md. Junaid,Yeasmin Akter,Aysha Siddika,S. M. Abdul Nayeem,Afsana Nahrin,Syeda Samira Afrose,Md. Muzahid Ahmed Ezaj,Muhammad Shaiful Alam
19F-NMR in Target-based Drug Discovery
Journal: Current Medicinal Chemistry
Volume: 26 Issue: 26 Year: 2019 Page: 4964-4983
Author(s): CongBao Kang
Preface [Hot topic: Hit-to-Lead: Driving Forces for the Medicinal Chemist (Guest Editor: Benoit Deprez and Rebecca Deprez-Poulain)]
Journal: Current Topics in Medicinal Chemistry
Volume: 4 Issue: 6 Year: 2004 Page: i-i
Author(s): Benoit Deprez, Rebecca Deprez-Poulain
Discovery and Hit to Lead Optimization of Novel Combretastatin A-4 Analogues: Dependence of C-Linker Length and Hybridization
Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 13 Issue: 10 Year: 2013 Page: 1614-1635
Author(s): Olivier Provot,Abdallah Hamze,Jean-François Peyrat,Jean-Daniel Brion,Mouad Alami
Facts, Figures and Trends in Lead Generation
Journal: Current Topics in Medicinal Chemistry
Volume: 4 Issue: 6 Year: 2004 Page: 569-580
Author(s): Rebecca Deprez-Poulain, Benoit Deprez