Search Result "early drug-discovery stage"


False Positives in the Early Stages of Drug Discovery

Journal: Current Medicinal Chemistry
Volume: 17 Issue: 3 Year: 2010 Page: 4231-4255
Author(s): R. Sink, S. Gobec, S. Pecar, A. Zega

Whole Organism Based Techniques and Approaches in Early Stage Oncology Drug Discovery-Patents and Trends

Journal: Recent Patents on Endocrine, Metabolic & Immune Drug Discovery
Volume: 5 Issue: 3 Year: 2011 Page: 183-191
Author(s): Richard J. Hampson, Michael D. Wyatt

Physicochemical Characterization of NCEs in Early Stage Drug Discovery

Ebook: Solubility, Delivery and ADME Problems of Drugs and Drug-Candidates
Volume: 1 Year: 2011
Author(s): Gyorgy T. Balogh
Doi: 10.2174/978160805120511101010033

Methodologies for Investigating Drug Metabolism at the Early Drug Discovery Stage: Prediction of Hepatic Drug Clearance and P450 Contribution

Journal: Current Drug Metabolism
Volume: 11 Issue: 8 Year: 2010 Page: 678-685
Author(s): Chie Emoto, Norie Murayama, Amin Rostami-Hodjegan, Hiroshi Yamazaki

ADME Optimization and Toxicity Assessment in Early- and Late-Phase Drug Discovery

Journal: Current Topics in Medicinal Chemistry
Volume: 9 Issue: 1 Year: 2009 Page: 965-980
Author(s): Gary W. Caldwell, Zhengyin Yan, Weimin Tang, Malini Dasgupta, Becki Hasting

Structural Biology in Early Phase Drug Discovery

Ebook: Young People’s Visions of the World
Volume: 1 Year: 2010
Author(s): Richard Alexander, John Spurlino
Doi: 10.2174/97816080519911050101

Modern Drug Discovery Technologies: Opportunities and Challenges in Lead Discovery

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 14 Issue: 1 Year: 2011 Page: 830-839
Author(s): Rafael V. C. Guido, Glaucius Oliva, Adriano D. Andricopulo

Failure and Success in Modern Drug Discovery: Guiding Principles in the Establishment of High Probability of Success Drug Discovery Organizations

Journal: Medicinal Chemistry
Volume: 1 Issue: 5 Year: 2005 Page: 519-527
Author(s): G. M. Rishton

Review Article

The In Silico Drug Discovery Toolbox: Applications in Lead Discovery and Optimization

Journal: Current Medicinal Chemistry
Volume: 26 Issue: 2 Year: 2019 Page: 3838-3873
Author(s): Agostino Bruno,Gabriele Costantino,Luca Sartori,Marco Radi

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