Search Result "cyclosarin (GF)"


In Silico Pharmacophore Modeling on Known Pyridinium Oxime Reactivators of Cyclosarin (GF) Inhibited AChE to Aid Discovery of Potential, More Efficacious Novel Non-Oxime Reactivators

Journal: Current Computer-Aided Drug Design
Volume: 9 Issue: 3 Year: 2013 Page: 402-411
Author(s): Apurba K. Bhattacharjee,Kamil Musilek,Kamil Kuca

Synthesis of Bisquaternary Symmetric - X,δ-Bis(2-Hydroxyiminomethylpyridinium) Alkane Dibromides and Their Reactivation of Cyclosarin-Inhibited Acetylcholinesterase

Journal: Letters in Organic Chemistry
Volume: 1 Issue: 1 Year: 2004 Page: 84-86
Author(s): Kamil Kuca, Jiri Cabal, Jiri Patocka, Jiri Kassa

Twelve Different HI-6 Salts and their Potency to Reactivate Cyclosarin Inhibited AChE In Vitro

Journal: Letters in Drug Design & Discovery
Volume: 4 Issue: 7 Year: 2007 Page: 510-512
Author(s): Kamil Kuca, Kamil Musilek, Petr Stodulka, Jan Marek, Petra Hanusova, Daniel Jun, Martina Hrabinova, Jiri Kassa, Bohuslav Dolezal

Structure-Activity Relationship of Acetylcholinesterase Reactivators -Antidotes Against Nerve Agents

Journal: Letters in Organic Chemistry
Volume: 4 Issue: 3 Year: 2007 Page: 212-217
Author(s): Kamil Kuca, Veronika Racakova, Daniel Jun, Jiri Bajgar

Journal: Letters in Drug Design & Discovery
Volume: 7 Issue: 7 Year: 2010 Page: 516-520
Author(s): Jana Zdarova Karasova, Jiri Kassa, Miroslav Pohanka, Kamil Musilek, Kamil Kuca

The Development of New Structural Analogues of Oximes for the Antidotal Treatment of Poisoning by Nerve Agents and the Comparison of Their Reactivating and Therapeutic Efficacy with Currently Available Oximes

Journal: Current Organic Chemistry
Volume: 11 Issue: 3 Year: 2007 Page: 267-283
Author(s): Jiri Kassa, Kamil Kuca, Lucie Bartosova, Gabriela Kunesova

Study of Efficacy of Reactivator HI-6 in Reactivation of Immobilized Acetylcholinesterase, Inhibited by Organophosphorus Chemical Warfare Agents of the “G” Series

Journal: Drug Metabolism Letters
Volume: 3 Issue: 1 Year: 2009 Page: 54-57
Author(s): Monika Hoskovcova, Emil Halamek, Zbynek Kobliha

Research Article

Oxime K033-Reactivation Activity of Cholinesterases Inhibited by Various Nerve Agents and Organophosphorus Pesticides

Journal: Letters in Drug Design & Discovery
Volume: 15 Issue: 11 Year: 2018 Page: 1124-1130
Author(s): Kamil Kuca,Kamil Musilek,Daniel Jun,Jaroslav Pejchal,Ondrej Krejcar,Marek Penhaker,Qinghua Wu,Raquel O. Lopes,Teodorico C. Ramalho,Tanos C.C. Franca,Eugenie Nepovimova,Ondrej Soukup

An In Silico Stereo-electronic Comparison of Conventional Pyridinium Oximes and K-oximes for Organophosphate (OP) Poisoning

Journal: Medicinal Chemistry
Volume: 8 Issue: 2 Year: 2012 Page: 230-245
Author(s): Apurba K. Bhattacharjee, Kamil Kuca, Kamil Musilek, Richard K. Gordon

Two Possibilities How to Increase the Efficacy of Antidotal Treatment of Nerve agent Poisonings

Journal: Mini-Reviews in Medicinal Chemistry
Volume: 12 Issue: 1 Year: 2012 Page: 24-34
Author(s): J. Kassa, K. Musilek, J. Zdarova Karasova, K. Kuca, J. Bajgar

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