Search Result "conformationally restricted analogues"


Initial Design and Synthesis of Conformationally Restricted and Pharmacophore-Based Scaffold Hopping Analogs of a Ras Pathway Modulator and Evaluation of Their MAPK Inhibitory Activities

Journal: Letters in Drug Design & Discovery
Volume: 3 Issue: 1 Year: 2006 Page: 44-48
Author(s): Sukumar Sakamuri, Quin-Zene Chen, Yingchun Lu, Yen-Fang Keng, Vladimir Khazak, Katrin Illgen, Silke Schabbert, Lutz Weber, Sanjay R. Menon

Development of Conformationally Restricted Analogues of Bradykinin and Somatostatin Using Constrained Amino Acids and Different Types of Cyclization

Journal: Current Medicinal Chemistry
Volume: 11 Issue: 2 Year: 2004 Page: 2823-2844
Author(s): Siegmund Reissmann, Diana Imhof

Review Article

The Use of Conformational Restriction in Medicinal Chemistry

Journal: Current Topics in Medicinal Chemistry
Volume: 19 Issue: 19 Year: 2019 Page: 1712-1733
Author(s): Pedro de Sena M. Pinheiro,Daniel A. Rodrigues,Rodolfo do Couto Maia,Sreekanth Thota,Carlos A.M. Fraga

Influence of Conformationally Constrained Amino Acids Replacing Positions 2 and 3 of Arginine Vasopressin (AVP) and Its Analogues on Their Pharmacological Properties

Journal: Protein & Peptide Letters
Volume: 14 Issue: 3 Year: 2007 Page: 213-217
Author(s): Dariusz Sobolewski, Adam Prahl, Izabela Derdowska, Anna Kwiatkowska, Jirina Slaninova, Bernard Lammek

Synthesis and Antiproliferative Effects of 5,6-Disubstituted Pyridazin-3(2H)-ones Designed as Conformationally Constrained Combretastatin A-4 Analogues

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 13 Issue: 7 Year: 2013 Page: 1133-1140
Author(s): Mohamed Elagawany, Martine Schmitt, Adel Ghiaty, A. Sh. El-Etrawy, Mohamed A. Ibrahim, Frederic Bihel, Aline Borba Sbardelotto, Claudia Pessoa, Tam Luong Nguyen, Ernest Hamel, Jean Jacques Bourguignon

Concise Synthesis of Non-Protein Amino Acid from Natural Product via Schmidt Reaction

Journal: Letters in Organic Chemistry
Volume: 6 Issue: 3 Year: 2009 Page: 186-188
Author(s): Kamila Gajcy, Tadeusz Librowski, Stanislaw Lochynski

Recent Developments in the Synthesis of Amino Acids and Analogues for Foldamers Study

Journal: Current Organic Synthesis
Volume: 5 Issue: 1 Year: 2008 Page: 61-80
Author(s): Debasish Haldar

Current Methods in Synthesis of Cyclic Oligonucleotides and Analogues

Journal: Current Organic Chemistry
Volume: 16 Issue: 11 Year: 2012 Page: 1371-1389
Author(s): Maria Gaglione,Giovanni Di Fabio,Anna Messere

A Role of GABA Analogues in the Treatment of Neurological Diseases

Journal: Current Medicinal Chemistry
Volume: 17 Issue: 2 Year: 2010 Page: 2338-2347
Author(s): K. Gajcy, S. Lochynski, T. Librowski

Recent Advances in Ligand-Based Drug Design: Relevance and Utility of the Conformationally Sampled Pharmacophore Approach

Journal: Current Computer-Aided Drug Design
Volume: 7 Issue: 1 Year: 2011 Page: 10-22
Author(s): Chayan Acharya, Andrew Coop, James E. Polli, Alexander D. MacKerell

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