Search Result "aspartic dyad"


Aspartic Proteases of Human Pathogenic Fungi are Prospective Targets for the Generation of Novel and Effective Antifungal Inhibitors

Journal: Current Enzyme Inhibition
Volume: 7 Issue: 2 Year: 2011 Page: 96-118
Author(s): Andre Luis Souza dos Santos

On the Active Site Protonation State in Aspartic Proteases: Implications for Drug Design

Journal: Current Pharmaceutical Design
Volume: 19 Issue: 2 Year: 2013 Page: 4257-4275
Author(s): Fredy Sussman, M. Carmen Villaverde, Jose L. Dominguez, U. Helena Danielson

Review Article

Dual BACE-1/GSK-3β Inhibitors to Combat Alzheimer's Disease: A Focused Review

Journal: Current Topics in Medicinal Chemistry
Volume: 17 Issue: 31 Year: 2017 Page: 3361-3369
Author(s): Angela Rampa,Silvia Gobbi,Rita Maria Concetta Di Martino,Federica Belluti,Alessandra Bisi

Conformationally Controlled Mechanistic Aspects of BACE 1 Inhibitors

Journal: Central Nervous System Agents in Medicinal Chemistry
Volume: 12 Issue: 1 Year: 2012 Page: 28-37
Author(s): M. Sonker, A. Yadav

Recent Advances in Plasmepsin Medicinal Chemistry and Implications for Future Antimalarial Drug Discovery Efforts

Journal: Current Topics in Medicinal Chemistry
Volume: 12 Issue: 5 Year: 2012 Page: 445-455
Author(s): Marvin J. Meyers, Daniel E. Goldberg

Fragment-based Designing for the Generation of Novel Leads Against BACE1

Journal: Central Nervous System Agents in Medicinal Chemistry
Volume: 15 Issue: 1 Year: 2015 Page: 52-64
Author(s): Sucharita Das,Sandipan Chakraborty,Soumalee Basu

Structure-Based β-Secretase (BACE1) Inhibitors

Journal: Current Pharmaceutical Design
Volume: 20 Issue: 20 Year: 2014 Page: 3373-3379
Author(s): Timea Polgar,Gyorgy M. Keseru

Expanding Targets for a Metabolic Therapy of Cancer: L-Asparaginase

Journal: Recent Patents on Anti-Cancer Drug Discovery
Volume: 7 Issue: 1 Year: 2012 Page: 4-13
Author(s): Daniele Covini, Saverio Tardito, Ovidio Bussolati, Laurent R. Chiarelli, Maria V. Pasquetto, Rita Digilio, Giovanna Valentini, Claudia Scotti

Review Article

Proteases in Mosquito Borne Diseases: New Avenues in Drug Development

Journal: Current Topics in Medicinal Chemistry
Volume: 17 Issue: 19 Year: 2017 Page: 2221-2232
Author(s): A. Pant,R. Pasupureddy,V. Pande,S. Seshadri,R. Dixit,K. C. Pandey

Structure-Based Design of Mucor pusillus Pepsin for the Improved Ratio of Clotting Activity/Proteolytic Activity in Cheese Manufacture

Journal: Protein & Peptide Letters
Volume: 22 Issue: 7 Year: 2015 Page: 660-667
Author(s): Jie Zhang, Yonghai Sun, Zhuolin Li, Quan Luo, Tiezhu Li, Tuoyi Wang

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