Search Result "allosteric mGluR PAM and NAM modulators."


Review Article

Fragment-Based Approaches for Allosteric Metabotropic Glutamate Receptor (mGluR) Modulators

Journal: Current Topics in Medicinal Chemistry
Volume: 19 Issue: 19 Year: 2019 Page: 1768-1781
Author(s): Zoltán Orgován,György G. Ferenczy,György M. Keserű

Allosteric Modulators for mGlu Receptors

Journal: Current Neuropharmacology
Volume: 5 Issue: 3 Year: 2007 Page: 187-194
Author(s): F. Gasparini, W. Spooren

Shining Light on an mGlu5 Photoswitchable NAM: A Theoretical Perspective

Journal: Current Neuropharmacology
Volume: 14 Issue: 5 Year: 2016 Page: 441-454
Author(s): James A.R. Dalton,Isaias Lans,Xavier Rovira,Fanny Malhaire,Xavier Gómez-Santacana,Silvia Pittolo,Pau Gorostiza,Amadeu Llebaria,Cyril Goudet,Jean-Philippe Pin,Jesús Giraldo

mGluR5 Positive and Negative Allosteric Modulators Differentially Affect Dendritic Spine Density and Morphology in the Prefrontal Cortex

Journal: CNS & Neurological Disorders - Drug Targets
Volume: 14 Issue: 4 Year: 2015 Page: 476-485
Author(s): Amber L. LaCrosse,Sara B. Taylor,Natali E. Nemirovsky,Justin T. Gass,Michael F. Olive

Metabotropic Glutamate Receptors as Targets for Analgesia: Antagonism, Activation, and Allosteric Modulation

Journal: Current Pharmaceutical Biotechnology
Volume: 12 Issue: 1 Year: 2011 Page: 1681-1688
Author(s): Michael C. Montana, Robert W. Gereau

Review Article

NMDAR PAMs: Multiple Chemotypes for Multiple Binding Sites

Journal: Current Topics in Medicinal Chemistry
Volume: 19 Issue: 24 Year: 2019 Page: 2239-2253
Author(s): Paul J. Goldsmith

Identification and Characterization of mGlu3 Ligands Using a High Throughput FLIPR Assay for Detection of Agonists, Antagonists, and Allosteric Modulators

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 14 Issue: 7 Year: 2011 Page: 631-641
Author(s): Steven D. Pratt, Mario Mezler, Herve Geneste, Margot H.M. Bakker, Philip J. Hajduk, Sujatha M. Gopalakrishnan

Chemical Biology of mGlu4 Receptor Activation: Dogmas, Challenges, Strategies and Opportunities

Journal: Current Topics in Medicinal Chemistry
Volume: 14 Issue: 15 Year: 2014 Page: 1755-1770
Author(s): Xinyan Huang,Elena Dale,Robbin M. Brodbeck,Dario Doller

Review Article

The Modulation of Pain by Metabotropic Glutamate Receptors 7 and 8 in the Dorsal Striatum

Journal: Current Neuropharmacology
Volume: 18 Issue: 1 Year: 2020 Page: 34-50
Author(s): Serena Boccella,Ida Marabese,Francesca Guida,Livio Luongo,Sabatino Maione,Enza Palazzo

The Therapeutic Potential of Allosteric Ligands for Free Fatty Acid Sensitive GPCRs

Journal: Current Topics in Medicinal Chemistry
Volume: 13 Issue: 1 Year: 2013 Page: 14-25
Author(s): Brian D. Hudson, Trond Ulven, Graeme Milligan

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