Search Result "Rac1 inhibitor"


Research Article

Preclinical Development of Novel Rac1-GEF Signaling Inhibitors using a Rational Design Approach in Highly Aggressive Breast Cancer Cell Lines

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 14 Issue: 6 Year: 2014 Page: 840-851
Author(s): Georgina A. Cardama,Maria J. Comin,Leandro Hornos,Nazareno Gonzalez,Lucas Defelipe,Adrian G. Turjanski,Daniel F. Alonso,Daniel E. Gomez,Pablo Lorenzano Menna

Research Article

MiR-485-5p Promotes Neuron Survival through Mediating Rac1/Notch2 Signaling Pathway after Cerebral Ischemia/Reperfusion

Journal: Current Neurovascular Research
Volume: 17 Issue: 3 Year: 2020 Page: 259-266
Author(s): Xuan Chen,Sumei Zhang,Peipei Shi,Yangli Su,Dong Zhang,Na Li

GEFT, A Rho Family Guanine Nucleotide Exchange Factor, Regulates Lens Differentiation through a Rac1-Mediated Mechanism

Journal: Current Molecular Medicine
Volume: 11 Issue: 6 Year: 2011 Page: 465-480
Author(s): D. C. Mitchell, B. A. Bryan, L. Liu, X.-H. Hu, X.-Q. Huang, W.-K. Ji, P.-C. Chen, W.-F. Hu, J-P Liu, J. Zhang, M. Liu, D. W.-C. Li

Pleiotropic Effect of Statins as Antioxidants on Cardiac Hypertrophy

Journal: Immunology, Endocrine & Metabolic Agents in Medicinal Chemistry
Volume: 8 Issue: 2 Year: 2008 Page: 167-171
Author(s): Hironori Nakagami, Ryuichi Morishita

Rac-1 as a New Therapeutic Target in Cerebro- and Cardio-Vascular Diseases

Journal: Current Drug Targets
Volume: 15 Issue: 13 Year: 2014 Page: 1231-1246
Author(s): Albino Carrizzo,Maurizio Forte,Maria Lembo,Luigi Formisano,Annibale A. Puca,Carmine Vecchione

Structure-Function Based Design of Small Molecule Inhibitors Targeting Rho Family GTPases

Journal: Current Topics in Medicinal Chemistry
Volume: 6 Issue: 1 Year: 2006 Page: 1109-1116
Author(s): Nicolas Nassar, Jose Cancelas, Jie Zheng, David A. Williams, Yi Zheng

Review Article

A Mechanistic Rationale for PDE-4 Inhibitors to Treat Residual Cognitive Deficits in Acquired Brain Injury

Journal: Current Neuropharmacology
Volume: 18 Issue: 3 Year: 2020 Page: 188-201
Author(s): Rudy Schreiber,Romain Hollands,Arjan Blokland

Nox Inhibitors & Therapies: Rational Design of Peptidic and Small Molecule Inhibitors

Journal: Current Pharmaceutical Design
Volume: 21 Issue: 41 Year: 2015 Page: 6032-6035
Author(s): M. Eugenia Cifuentes-Pagano,Daniel N. Meijles,Patrick J. Pagano

Targeting Neurite Growth Inhibitors to Induce CNS Regeneration

Journal: Current Pharmaceutical Design
Volume: 11 Issue: 1 Year: 2005 Page: 1247-1253
Author(s): Abba J. Kastin, Weihong Pan

Therapeutic Potentials of Recently Identified PLD Inhibitors

Journal: Current Chemical Biology
Volume: 4 Issue: 3 Year: 2010 Page: 244-249
Author(s): Nicolas Vitale

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