Search Result "RT binding pockets and novel inhibitors"


Research Article

Identification of Adjacent NNRTI Binding Pocket in Multi-mutated HIV1- RT Enzyme Model: An in silico Study

Journal: Current HIV Research
Volume: 16 Issue: 2 Year: 2018 Page: 121-129
Author(s): R.F. Kamil,U. Debnath,S. Verma,Y.S. Prabhakar

Molecular Aspects of the RT/drug Interactions. Perspective of Dual Inhibitors

Journal: Current Pharmaceutical Design
Volume: 19 Issue: 10 Year: 2013 Page: 1850-1859
Author(s): Simona Distinto,Elias Maccioni,Rita Meleddu,Angela Corona,Stefano Alcaro,Enzo Tramontano

HIV-1 RT Nonnucleoside Inhibitors and Their Interaction with RT for Antiviral Drug Development

Journal: Infectious Disorders - Drug Targets
Volume: 6 Issue: 4 Year: 2006 Page: 391-413
Author(s): Zhigang Zhou, Xin Lin, Jeffry D. Madura

Impact of Residues in the Nonnucleoside Reverse Transcriptase Inhibitor Binding Pocket on HIV-1 Reverse Transcriptase Heterodimer Stability

Journal: Current HIV Research
Volume: 6 Issue: 2 Year: 2008 Page: 130-137
Author(s): Anna Figueiredo, Shannon Zelina, Nicolas Sluis-Cremer, Gilda Tachedjian

Multiple Allosteric Pockets of HCV NS5B Polymerase and its Inhibitors: A Structure Based Insight

Journal: Current Bioactive Compounds
Volume: 4 Issue: 2 Year: 2008 Page: 86-109
Author(s): Tanaji T. Talele

Conformational Changes in HIV-1 Reverse Transcriptase Induced by Nonnucleoside Reverse Transcriptase Inhibitor Binding

Journal: Current HIV Research
Volume: 2 Issue: 4 Year: 2004 Page: 323-332
Author(s): Nicolas Sluis-Cremer, N. Alpay Temiz, Ivet Bahar

Novel Broad-Spectrum Thiourea Non-Nucleoside Inhibitors for the Prevention of Mucosal HIV Transmission

Journal: Current HIV Research
Volume: 4 Issue: 3 Year: 2006 Page: 329-345
Author(s): Osmond J. DCruz, Fatih M. Uckun

Design Strategies of Novel NNRTIs to Overcome Drug Resistance

Journal: Current Medicinal Chemistry
Volume: 16 Issue: 2 Year: 2009 Page: 3903-3917
Author(s): Peng Zhan, Xinyong Liu, Zhenyu Li, Christophe Pannecouque, Erik De Clercq

Selectivity, Binding Affinity, and Ionization State of Matrix Metalloproteinase Inhibitors

Journal: Current Pharmaceutical Design
Volume: 19 Issue: 26 Year: 2013 Page: 4701-4713
Author(s): Haizhen A. Zhong,Jack Arbiser,J. Phillip Bowen

Current Status of the Non-nucleoside Reverse Transcriptase Inhibitors of Human Immunodeficiency Virus Type 1

Journal: Current Topics in Medicinal Chemistry
Volume: 4 Issue: 9 Year: 2004 Page: 921-944
Author(s): J. Balzarini

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