Search Result "Plasma clearance"


Prediction of Human Hepatic Clearance Using an In Vitro Plated Hepatocyte Clearance Model

Journal: Drug Metabolism Letters
Volume: 3 Issue: 4 Year: 2009 Page: 296-307
Author(s): Piyun Chao, Jeffrey Barminko, Eric Novik, Yi Han, Timothy Maguire, K.-C. Cheng

Impact of Input Parameters on the Prediction of Hepatic Plasma Clearance Using the Well-Stirred Model

Journal: Current Drug Metabolism
Volume: 11 Issue: 7 Year: 2010 Page: 583-594
Author(s): Hong Wan, Peter Bold, Lars-Olof Larsson, Johan Ulander, Sheila Peters, Boel Lofberg, Anna-Lena Ungell, Mats Nagard, Antonio Llinas

Review Article

Optimization of Protein and Peptide Drugs Based on the Mechanisms of Kidney Clearance

Journal: Protein & Peptide Letters
Volume: 25 Issue: 6 Year: 2018 Page: 514-521
Author(s): Huizi Wu,Jiaguo Huang

Application of Organ Clearance to Estimation of the In Vivo Hepatic Extraction Ratio

Journal: Current Clinical Pharmacology
Volume: 11 Issue: 1 Year: 2016 Page: 47-52
Author(s): Reza Mehvar

Predicting Clearance in Humans from In Vitro Data

Journal: Current Topics in Medicinal Chemistry
Volume: 11 Issue: 4 Year: 2011 Page: 334-339
Author(s): R. Scott Obach

Do We Need to Optimize Plasma Protein and Tissue Binding in Drug Discovery?

Journal: Current Topics in Medicinal Chemistry
Volume: 11 Issue: 4 Year: 2011 Page: 450-466
Author(s): Xingrong Liu, Cuiping Chen, Cornelis E.C.A. Hop

Research Article

The Role of Aldehyde Oxidase in the Metabolic Clearance of Substituted Benzothiazoles

Journal: Drug Metabolism Letters
Volume: 14 Issue: 2 Year: 2021 Page: 126-136
Author(s): Yohannes Teffera,Jingzhou Liu,Paul Krolikowski,Zhiyang Zhao

Modification of Clearance of Therapeutic and Potentially Therapeutic Proteins

Journal: Current Drug Targets - Cardiovascular & Hematological Disorders
Volume: 1 Issue: 1 Year: 2001 Page: 1-22
Author(s): W. P. Sheffield

Apoptotic Cell Clearance and Autoimmune Disorder

Journal: Current Medicinal Chemistry
Volume: 14 Issue: 2 Year: 2007 Page: 2892-2897
Author(s): Masato Tanaka, Yasunobu Miyake

ARC - Augmented Renal Clearance

Journal: Current Pharmaceutical Biotechnology
Volume: 12 Issue: 1 Year: 2011 Page: 2020-2029
Author(s): Andrew A. Udy, Michael T. Putt, Robert J. Boots, Jeffrey Lipman

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