Search Result "PXR-knockout HepaRG cells"
Cytochrome P450 1A2 Messenger RNA is a More Reliable Marker than Cytochrome P450 1A2 Activity, Phenacetin O-Deethylation, for Assessment of Induction Potential of Drug-Metabolizing Enzymes Using HepaRG Cells
Journal: Drug Metabolism Letters
Volume: 12 Issue: 1 Year: 2018 Page: 14-23
Author(s): Akira Ogasawara,Nozomu Kato,Nao Torimoto,Fumika Aohara,Rikiya Ohashi,Yasuhiro Yamada,Hideki Taniguchi
Hepatic Cell Lines for Drug Hepatotoxicity Testing: Limitations and Strategies to Upgrade their Metabolic Competence by Gene Engineering
Journal: Current Drug Metabolism
Volume: 14 Issue: 9 Year: 2013 Page: 946-968
Author(s): M. Teresa Donato,Ramiro Jover,M. José Gómez-Lechón
New Insight into P-Glycoprotein as a Drug Target
Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 13 Issue: 1 Year: 2013 Page: 159-170
Author(s): Albert Breier,Lenka Gibalova,Mario Seres,Miroslav Barancik,Zdenka Sulova
Enzyme Induction: Translating Multiple Approaches, Assays, Endpoints, and Opinions into a Valuable Induction Screening Strategy
Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 13 Issue: 2 Year: 2010 Page: 135-144
Author(s): Adrian Fretland, Mario Monshouwer
Emerging In Vitro Tools to Evaluate Cytochrome P450 and Transporter-Mediated Drug-Drug Interactions
Journal: Current Drug Discovery Technologies
Volume: 7 Issue: 3 Year: 2010 Page: 199-222
Author(s): Cormac Concannon, Desmond A. Hennelly, Simon Noott, Dipak K. Sarker, Chuang Lu, Mingxiang Liao, Lawrence Cohen, Cindy Q. Xia
The Role of Xenobiotic Receptors on Hepatic Glycolipid Metabolism
Journal: Current Drug Metabolism
Volume: 20 Issue: 1 Year: 2019 Page: 29-35
Author(s): Ke Chen,Jinwei Zhong,Lin Hu,Ruliu Li,Qun Du,Jiazhong Cai,Yanwu Li,Yong Gao,Xiaona Cui,Xiaoying Yang,Xiaojie Wu,Lu Yao,Juji Dai,Yan Wang,Haiyong Jin
Xenosensors CAR and PXR at Work: Impact on Statin Metabolism
Journal: Current Drug Metabolism
Volume: 12 Issue: 3 Year: 2011 Page: 300-311
Author(s): Maria Marino, Alessandra di Masi, Viviana Trezza, Valentina Pallottini, Fabio Polticelli, Paolo Ascenzi