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A Multicenter, Double-Blind, Placebo-Controlled Trial of the PDE9A Inhibitor, PF-04447943, in Alzheimers Disease

Journal: Current Alzheimer Research
Volume: 11 Issue: 5 Year: 2014 Page: 413-421
Author(s): Elias M. Schwam, Timothy Nicholas, Robert Chew, Clare B. Billing, Wendy Davidson, Darlene Ambrose, Larry D. Altstiel

Phosphodiesterase Inhibitors as a Target for Cognition Enhancement in Aging and Alzheimer’s Disease: A Translational Overview

Journal: Current Pharmaceutical Design
Volume: 21 Issue: 3 Year: 2015 Page: 317-331
Author(s): P.R.A. Heckman,C. Wouters,J. Prickaerts

Mining ZINC Database to Discover Potential Phosphodiesterase 9 Inhibitors Using Structure-Based Drug Design Approach

Journal: Medicinal Chemistry
Volume: 12 Issue: 5 Year: 2016 Page: 472-477
Author(s): Engi A. Hassaan,Sara C. Sigler,Tamer M. Ibrahim,Kevin J. Lee,Lauren K. Cichon,Bernard D. Gary,Joshua C. Canzoneri,Gary A. Piazza,Ashraf H.Abadi

Phosphodiesterase as a Target for Cognition Enhancement in Schizophrenia

Journal: Current Topics in Medicinal Chemistry
Volume: 20 Issue: 26 Year: 2020 Page: 2404-2421
Author(s): Mayasah Y. Al-Nema,Anand Gaurav

Phosphodiesterase: An Interface Connecting Cognitive Deficits to Neuropsychiatric and Neurodegenerative Diseases

Journal: Current Pharmaceutical Design
Volume: 21 Issue: 3 Year: 2015 Page: 303-316
Author(s): Zhen-Zhen Wang,Yi Zhang,Han-Ting Zhang,Yun-Feng Li

Treatment of Cognitive Impairment in Schizophrenia: Potential Value of Phosphodiesterase Inhibitors in Prefrontal Dysfunction

Journal: Current Pharmaceutical Design
Volume: 21 Issue: 26 Year: 2015 Page: 3813-3828
Author(s): Marlies Van Duinen,Olga A.H. Reneerkens,Lena Lambrecht,Anke Sambeth,Bart P.F. Rutten,Jim Van Os,Arjan Blokland,Jos Prickaerts

Identification of Xanthine Derivatives as Inhibitors of Phosphodiesterase 9A Through In silico and Biological Studies

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 21 Issue: 7 Year: 2018 Page: 476-486
Author(s): Nivedita Singh,Swagata Patra,Sanjukta Patra

Alzheimer's Disease: A Systemic Review of Substantial Therapeutic Targets and the Leading Multi-functional Molecules

Journal: Current Topics in Medicinal Chemistry
Volume: 17 Issue: 31 Year: 2017 Page: 3370-3389
Author(s): Tarana Umar,Nasimul Hoda

Pharmacotherapies for Alzheimer’s Disease: From Natural Compounds to Target Synthetic Drugs

Ebook: Frontiers in Clinical Drug Research - Alzheimer Disorders
Volume: 1 Year: 2013
Author(s): Chuang Wang,Rui Wang,James M. O’Donnell,Ying Xu
Doi: 10.2174/9781608057221113010011

Journal: Current Medicinal Chemistry
Volume: 23 Issue: 2 Year: 2016 Page: 2770-2788
Author(s): Manel Ben Aissa, Sue H. Lee, Brian M. Bennett, Gregory R.J. Thatcher