Search Result "PERK inhibitors"


Research Article

Use of Small-molecule Inhibitory Compound of PERK-dependent Signaling Pathway as a Promising Target-based Therapy for Colorectal Cancer

Journal: Current Cancer Drug Targets
Volume: 20 Issue: 3 Year: 2020 Page: 223-238
Author(s): Wioletta Rozpędek,Dariusz Pytel,Adam Wawrzynkiewicz,Natalia Siwecka,Adam Dziki,Łukasz Dziki,J. Alan Diehl,Ireneusz Majsterek

PERK-opathies: An Endoplasmic Reticulum Stress Mechanism Underlying Neurodegeneration

Journal: Current Alzheimer Research
Volume: 13 Issue: 2 Year: 2016 Page: 150-163
Author(s): Michelle C. Bell,Shelby E. Meier,Alexandria L. Ingram,Jose F. Abisambra

Research Article

Inhibition of the PERK-Dependent Unfolded Protein Response Signaling Pathway Involved in the Pathogenesis of Alzheimer’s Disease

Journal: Current Alzheimer Research
Volume: 16 Issue: 3 Year: 2019 Page: 209-218
Author(s): Wioletta Rozpędek,Dariusz Pytel,Tomasz Popławski,Anna Walczak,Kinga Gradzik,Adam Wawrzynkiewicz,Radosław Wojtczak,Bartosz Mucha,John Alan Diehl,Ireneusz Majsterek

Unfolded Protein Response and PERK Kinase as a New Therapeutic Target in the Pathogenesis of Alzheimer’s Disease

Journal: Current Medicinal Chemistry
Volume: 22 Issue: 27 Year: 2015 Page: 3169-3184
Author(s): Wioletta Rozpedek,Lukasz Markiewicz,J. Alan Diehl,Dariusz Pytel,Ireneusz Majsterek

Review Article

Molecular Basis of Human Diseases and Targeted Therapy Based on Small-Molecule Inhibitors of ER Stress-Induced Signaling Pathways

Journal: Current Molecular Medicine
Volume: 17 Issue: 2 Year: 2017 Page: 118-132
Author(s): W. Rozpedek,A. Nowak,D. Pytel,J. Alan Diehl,I. Majsterek

Review Article

Breaking the DNA Damage Response via Serine/Threonine Kinase Inhibitors to Improve Cancer Treatment

Journal: Current Medicinal Chemistry
Volume: 26 Issue: 8 Year: 2019 Page: 1425-1445
Author(s): Wioletta Rozpędek,Dariusz Pytel,Alicja Nowak-Zduńczyk,Dawid Lewko,Radosław Wojtczak,J. Alan Diehl,Ireneusz Majsterek

Review Article

The Role of the PERK/eIF2α/ATF4/CHOP Signaling Pathway in Tumor Progression During Endoplasmic Reticulum Stress

Journal: Current Molecular Medicine
Volume: 16 Issue: 6 Year: 2016 Page: 533-544
Author(s): W. Rozpedek, D. Pytel, B. Mucha, H. Leszczynska, J.A. Diehl, I. Majsterek

Antidepressant Desipramine Leads to C6 Glioma Cell Autophagy: Implication for the Adjuvant Therapy of Cancer

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 13 Issue: 2 Year: 2013 Page: 254-260
Author(s): Jian Ma,Li-Na Hou,Zheng-Xing Rong,Peng Liang,Chao Fang,Hua-Fang Li,Hong Qi,Hong-Zhuan Chen

Review Article

Pyrrolo[2,3-d]Pyrimidines as Kinase Inhibitors

Journal: Current Medicinal Chemistry
Volume: 24 Issue: 19 Year: 2017 Page: 2059-2085
Author(s): Francesca Musumeci,Monica Sanna,Giancarlo Grossi,Chiara Brullo,Anna Lucia Fallacara,Silvia Schenone

Heat Shock Protein 90 Inhibitors in Oncology

Journal: Current Proteomics
Volume: 11 Issue: 1 Year: 2014 Page: 2-16
Author(s): Aykut Ozgur, Yusuf Tutar

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