Search Result "PAMS"


Research Article

Characterization of a New Positive Allosteric Modulator of AMPA Receptors - PAM-43: Specific Binding of the Ligand and its Ability to Potentiate AMPAR Currents

Journal: Current Molecular Pharmacology
Volume: 13 Issue: 3 Year: 2020 Page: 216-223
Author(s): Tatiana V. Vyunova,Lioudmila A. Andreeva,Konstantin V. Shevchenko,Vladimir V. Grigoriev,Vladimir A. Palyulin,Mstislav I. Lavrov,Ekaterina V. Bondarenko,Elena E. Kalashnikova,Nikolay F. Myasoedov

Review Article

NMDAR PAMs: Multiple Chemotypes for Multiple Binding Sites

Journal: Current Topics in Medicinal Chemistry
Volume: 19 Issue: 24 Year: 2019 Page: 2239-2253
Author(s): Paul J. Goldsmith

SAR Studies on Carboxylic Acid Series M1 Selective Positive Allosteric Modulators (PAMs)

Journal: Current Topics in Medicinal Chemistry
Volume: 14 Issue: 15 Year: 2014 Page: 1738-1754
Author(s): Scott D. Kuduk,Douglas C. Beshore

Research Article

Effects of Plasma Activated Medium on Head and Neck FaDu Cancerous Cells: Comparison of 3D and 2D Response

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 18 Issue: 6 Year: 2018 Page: 776-783
Author(s): Julie Chauvin,Florian Judee,Nofel Merbahi,Patricia Vicendo

A Generalized Model and High Throughput Data Analysis System for Functional Modulation of Receptor-Agonist Systems Suitable for use in Drug Discovery

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 16 Issue: 3 Year: 2013 Page: 199-209
Author(s): Aaron C. Pawlyk,R. Kyle Palmer,Dennis Sprous,Chip Allee

Research Article

Reactivation Potential of Novel More Lipophilic Pralidoxime Analogs

Journal: Letters in Drug Design & Discovery
Volume: 15 Issue: 8 Year: 2018 Page: 822-827
Author(s): Martina Hrabinova,Jan Misik,Daniel Jun,Kamil Kuca

Review Article

The Potential of PI3K/AKT/mTOR Signaling as a Druggable Target for Endometrial and Ovarian Carcinomas

Journal: Current Drug Targets
Volume: 21 Issue: 10 Year: 2020 Page: 946-961
Author(s): Csongor György Lengyel,Sara Cecilia Altuna,Baker Shalal Habeeb,Dario Trapani,Shah Zeb Khan

Letter Article open access plus

Challenges in the Discovery and Optimization of mGlu2/4 Heterodimer Positive Allosteric Modulators

Journal: Letters in Drug Design & Discovery
Volume: 16 Issue: 12 Year: 2019 Page: 1387-1394
Author(s): Mark Gallant Fulton,Matthew Thomas Loch,Caroline Anne Cuoco,Alice Lambert Rodriguez,Emily Days,Paige Newton Vinson,Krystian Andrezej Kozek,Charles David Weaver,Anna Louise Blobaum,Peter Jeffrey Conn,Colleen Marie Niswender,Craig William Lindsley

Advances in the Discovery of Novel Positive Allosteric Modulators of the α7 Nicotinic Acetylcholine Receptor

Journal: Recent Patents on CNS Drug Discovery (Discontinued)
Volume: 2 Issue: 2 Year: 2007 Page: 99-106
Author(s): Ramin Faghih, Gregory A. Gfesser, Murali Gopalakrishnan

SAR Studies on mGlu5 Receptor Positive Allosteric Modulators (2003- 2013)

Journal: Current Topics in Medicinal Chemistry
Volume: 14 Issue: 15 Year: 2014 Page: 1789-1841
Author(s): Junliang Hao,Hui Xiong

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