Search Result "Orthosteric site"


Review Article

Insights into the Structural Aspects of the mGlu Receptor Orthosteric Binding Site

Journal: Current Topics in Medicinal Chemistry
Volume: 19 Issue: 2 Year: 2019 Page: 2421-2446
Author(s): Junliang Hao,Qi Chen

The Different Ways through Which Specificity Works in Orthosteric and Allosteric Drugs

Journal: Current Pharmaceutical Design
Volume: 18 Issue: 9 Year: 2012 Page: 1311-1316
Author(s): Ruth Nussinov, Chung-Jung Tsai

Allosteric Modulators for Adenosine Receptors: An Alternative to the Orthosteric Ligands

Journal: Current Topics in Medicinal Chemistry
Volume: 10 Issue: 1 Year: 2010 Page: 976-992
Author(s): C. La Motta, S. Sartini, M. Morelli, S. Taliani, F. Da Settimo

Druggable Orthosteric and Allosteric Hot Spots to Target Protein-protein Interactions

Journal: Current Pharmaceutical Design
Volume: 20 Issue: 8 Year: 2014 Page: 1293-1301
Author(s): Buyong Ma, Ruth Nussinov

Medicinal Chemistry of P2X Receptors: Agonists and Orthosteric Antagonists

Journal: Current Medicinal Chemistry
Volume: 22 Issue: 7 Year: 2015 Page: 915-928
Author(s): Catia Lambertucci,Diego Dal Ben,Michela Buccioni,Gabriella Marucci,Ajiroghene Thomas,Rosaria Volpini

Review Article

Recent Advances in the Drug Discovery and Development of Dualsteric/ Bitopic Activators of G Protein-Coupled Receptors

Journal: Current Topics in Medicinal Chemistry
Volume: 19 Issue: 2 Year: 2019 Page: 2378-2392
Author(s): Bethany A. Reinecke,Huiqun Wang,Yan Zhang

Allosteric Modulators of the Human Calcium-Sensing Receptor:Structures, Sites of Action, and Therapeutic Potentials

Journal: Endocrine, Metabolic & Immune Disorders - Drug Targets
Volume: 8 Issue: 3 Year: 2008 Page: 192-197
Author(s): Jianxin Hu

Review Article

Molecular Basis of Modulating Adenosine Receptors Activities

Journal: Current Pharmaceutical Design
Volume: 25 Issue: 7 Year: 2019 Page: 817-831
Author(s): Mohammed Nooraldeen Mahmod Al-Qattan,Mohd Nizam Mordi

The Therapeutic Potential of Allosteric Ligands for Free Fatty Acid Sensitive GPCRs

Journal: Current Topics in Medicinal Chemistry
Volume: 13 Issue: 1 Year: 2013 Page: 14-25
Author(s): Brian D. Hudson, Trond Ulven, Graeme Milligan

Review Article

The Two Faces of Protein Flexibility: A Topological Approach

Journal: Current Chemical Biology
Volume: 12 Issue: 1 Year: 2018 Page: 14-22
Author(s): Luisa Di Paola,Alessandro Giuliani

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