Search Result "Negative allosteric modulator(NAM)"


Shining Light on an mGlu5 Photoswitchable NAM: A Theoretical Perspective

Journal: Current Neuropharmacology
Volume: 14 Issue: 5 Year: 2016 Page: 441-454
Author(s): James A.R. Dalton,Isaias Lans,Xavier Rovira,Fanny Malhaire,Xavier Gómez-Santacana,Silvia Pittolo,Pau Gorostiza,Amadeu Llebaria,Cyril Goudet,Jean-Philippe Pin,Jesús Giraldo

Allosteric Modulators for mGlu Receptors

Journal: Current Neuropharmacology
Volume: 5 Issue: 3 Year: 2007 Page: 187-194
Author(s): F. Gasparini, W. Spooren

Review Article

Tuning Down the Pain – An Overview of Allosteric Modulation of Opioid Receptors: Mechanisms of Modulation, Allosteric Sites, Modulator Syntheses

Journal: Current Topics in Medicinal Chemistry
Volume: 20 Issue: 31 Year: 2020 Page: 2852-2865
Author(s): Damian Bartuzi,Tomasz M. Wróbel,Agnieszka A. Kaczor,Dariusz Matosiuk

Research Article

Medicinal Chemistry of P2X Receptors: Allosteric Modulators

Journal: Current Medicinal Chemistry
Volume: 22 Issue: 7 Year: 2015 Page: 929-941
Author(s): Christa E. Muller

Review Article

Recent Developments in Group I Metabotropic Glutamate Receptor Allosteric Modulators for the Treatment of Psychiatric and Neurological Disorders (2014-May 2015)

Journal: Current Topics in Medicinal Chemistry
Volume: 16 Issue: 2 Year: 2016 Page: 3470-3526
Author(s): Guiying Li, Morten Jorgensen, Brian M. Campbell, Dario Doller

mGluR5 Negative Allosteric Modulators Overview: A Medicinal Chemistry Approach Towards a Series of Novel Therapeutic Agents

Journal: Current Topics in Medicinal Chemistry
Volume: 11 Issue: 6 Year: 2011 Page: 680-695
Author(s): Jean-Philippe Rocher, Beatrice Bonnet, Christelle Bolea, Robert Lutjens, Emmanuel Le Poul, Sonia Poli, Mark Epping-Jordan, Anne-Sophie Bessis, Bernard Ludwig, Vincent Mutel

mGluR5 Positive and Negative Allosteric Modulators Differentially Affect Dendritic Spine Density and Morphology in the Prefrontal Cortex

Journal: CNS & Neurological Disorders - Drug Targets
Volume: 14 Issue: 4 Year: 2015 Page: 476-485
Author(s): Amber L. LaCrosse,Sara B. Taylor,Natali E. Nemirovsky,Justin T. Gass,Michael F. Olive

Review Article

Fragment-Based Approaches for Allosteric Metabotropic Glutamate Receptor (mGluR) Modulators

Journal: Current Topics in Medicinal Chemistry
Volume: 19 Issue: 19 Year: 2019 Page: 1768-1781
Author(s): Zoltán Orgován,György G. Ferenczy,György M. Keserű

Review Article

Potential for the Rational Design of Allosteric Modulators of Class C GPCRs

Journal: Current Topics in Medicinal Chemistry
Volume: 17 Issue: 1 Year: 2017 Page: 71-78
Author(s): John A. Christopher,Andrew S. Doré,Benjamin G. Tehan

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