Search Result "NSC23766"


Structure-Function Based Design of Small Molecule Inhibitors Targeting Rho Family GTPases

Journal: Current Topics in Medicinal Chemistry
Volume: 6 Issue: 1 Year: 2006 Page: 1109-1116
Author(s): Nicolas Nassar, Jose Cancelas, Jie Zheng, David A. Williams, Yi Zheng

Signaling Through Rho GTPase Pathway as Viable Drug Target

Journal: Current Medicinal Chemistry
Volume: 16 Issue: 1 Year: 2009 Page: 1355-1365
Author(s): Qun Lu, Frank M. Longo, Huchen Zhou, Stephen M. Massa, Yan-Hua Chen

Rac-1 as a New Therapeutic Target in Cerebro- and Cardio-Vascular Diseases

Journal: Current Drug Targets
Volume: 15 Issue: 13 Year: 2014 Page: 1231-1246
Author(s): Albino Carrizzo,Maurizio Forte,Maria Lembo,Luigi Formisano,Annibale A. Puca,Carmine Vecchione

Novel Pharmacologic Approaches to the Prevention and Treatment of Ulcerative Colitis

Journal: Current Pharmaceutical Design
Volume: 19 Issue: 1 Year: 2013 Page: 17-28
Author(s): Xiaoming Deng,Sandor Szabo,Tetyana Khomenko,Ganna Tolstanova,Brankica Paunovic,Samuel W. French,Zsuzsanna Sandor

GEFT, A Rho Family Guanine Nucleotide Exchange Factor, Regulates Lens Differentiation through a Rac1-Mediated Mechanism

Journal: Current Molecular Medicine
Volume: 11 Issue: 6 Year: 2011 Page: 465-480
Author(s): D. C. Mitchell, B. A. Bryan, L. Liu, X.-H. Hu, X.-Q. Huang, W.-K. Ji, P.-C. Chen, W.-F. Hu, J-P Liu, J. Zhang, M. Liu, D. W.-C. Li

Research Article

Preclinical Development of Novel Rac1-GEF Signaling Inhibitors using a Rational Design Approach in Highly Aggressive Breast Cancer Cell Lines

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 14 Issue: 6 Year: 2014 Page: 840-851
Author(s): Georgina A. Cardama,Maria J. Comin,Leandro Hornos,Nazareno Gonzalez,Lucas Defelipe,Adrian G. Turjanski,Daniel F. Alonso,Daniel E. Gomez,Pablo Lorenzano Menna

Targeting Rho GTPases by Peptidic Structures

Journal: Current Pharmaceutical Design
Volume: 15 Issue: 2 Year: 2009 Page: 2481-2487
Author(s): Filippo Marchioni, Yi Zheng

Past, Present, and Future of Targeting Ras for Cancer Therapies

Journal: Mini-Reviews in Medicinal Chemistry
Volume: 16 Issue: 5 Year: 2016 Page: 345-357
Author(s): Zhi Tan,Shuxing Zhang

Transactivation of EGFR by G Protein-Coupled Receptor in the Pathophysiology of Intimal Hyperplasia

Journal: Current Vascular Pharmacology
Volume: 12 Issue: 2 Year: 2014 Page: 190-201
Author(s): Swastika Sur,Devendra K. Agrawal

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