Search Result "Maximum Tolerated Dose"


A Randomized, Double-Blind, Placebo-Controlled Pilot Trial of Safety and Tolerability of Two Doses of Divalproex Sodium in Outpatients with Probable Alzheimers Disease

Journal: Current Alzheimer Research
Volume: 2 Issue: 5 Year: 2005 Page: 553-558
Author(s): Louis A. Profenno, Laura Jakimovich, Connie J. Holt, Anton Porsteinsson, Pierre N. Tariot

Efficacy and Tolerability of Vinorelbine in the Cancer Therapy

Journal: Current Drug Safety
Volume: 6 Issue: 3 Year: 2011 Page: 185-193
Author(s): Giuseppina Galano, Mariella Caputo, Mario Felice Tecce, Anna Capasso

Induction of Tolerance in Children with Food Allergy

Journal: Current Nutrition & Food Science
Volume: 7 Issue: 1 Year: 2011 Page: 33-39
Author(s): Marta Reche, Teresa Valbuena, Ana Fiandor, Antonia Padial, Santiago Quirce, Cristina Pascual

Review Article

Poor Safety and Tolerability Hamper Reaching a Potentially Therapeutic Dose in the Use of Thalidomide for Alzheimer’s Disease: Results from a Double-Blind, Placebo-Controlled Trial

Journal: Current Alzheimer Research
Volume: 14 Issue: 4 Year: 2017 Page: 403-411
Author(s): Boris Decourt,Denise Drumm-Gurnee,Jeffrey Wilson,Sandra Jacobson,Christine Belden,Sherye Sirrel,Michael Ahmadi,Holly Shill,Jessica Powell,Aaron Walker,Amanda Gonzales,Mimi Macias,Marwan N. Sabbagh

Impaired Autophagy Mediates Resistance to Low-Dose Metronomic Cyclophosphamide Chemotherapy

Journal: Clinical Cancer Drugs
Volume: 1 Issue: 2 Year: 2014 Page: 116-126
Author(s): Annabelle Chow,Giulio Francia,Andrew Kouri,Christina Lee,John M. Ebos,Robert S. Kerbel,Urban Emmenegger

Assessment of the Health Effects of Chemicals in Humans: I. QSAR Estimation of the Maximum Recommended Therapeutic Dose (MRTD) and No Effect Level (NOEL) of Organic Chemicals Based on Clinical Trial Data1

Journal: Current Drug Discovery Technologies
Volume: 1 Issue: 1 Year: 2004 Page: 61-76
Author(s): Edwin J. Matthews, Naomi L. Kruhlak, R. Daniel Benz, Joseph F. Contrera

Single-dose Pharmacokinetics and Tolerability of Oral Delta-9- Tetrahydrocannabinol in Patients with Amyotrophic Lateral Sclerosis

Journal: Drug Metabolism Letters
Volume: 6 Issue: 2 Year: 2012 Page: 102-108
Author(s): Markus Joerger,Justin Wilkins,Stefania Fagagnini,Reto Baldinger,Rudolf Brenneisen,Ursula Schneider,Bea Goldman,Markus Weber

Pharmacometrics in Dose Finding or Dose Optimization of Anti-Retroviral and Anti-Tubercular Drugs

Journal: Infectious Disorders - Drug Targets
Volume: 11 Issue: 2 Year: 2011 Page: 157-166
Author(s): Sreedharan Nair Sabarinath, Benjamin Wu, Charles Peloquin, Hartmut Derendorf

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single and Repeat Doses of GW870086: Two Randomised Studies

Journal: Current Drug Therapy
Volume: 8 Issue: 2 Year: 2013 Page: 76-85
Author(s): Ann Allen, Philippe Bareille, Kelly Hardes, Jonathan Robertson

Clinical Trial open access plus

A Phase I Study of OMN54 (Aneustat™) in Patients with Advanced Malignancies

Journal: Clinical Cancer Drugs
Volume: 7 Issue: 2 Year: 2020 Page: 125-132
Author(s): Karen A. Gelmon,Christian Kollmannsberger,Stephen Chia,Anna V. Tinker,Teresa Mitchell,Stephen Lam,Teresa Joshi,David Kwok,John Ostrem,Simon Sutcliffe,Daniel J. Renouf

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