Search Result "MGMT inhibitors"


Review Article

Current Translational Insights into MGMT Methylation Regulating Temozolomide Sensitivity and Resistance in Glioblastoma Multiforme

Journal: Current Pharmacogenomics and Personalized Medicine
Volume: 17 Issue: 2 Year: 2020 Page: 76-93
Author(s): Ishmeet Gulati,Harsh Patel,Bala Prabhakar,Sujit Nair

Genetic Variation at the Human MGMT Locus and its Biological Consequences

Journal: Current Pharmacogenomics
Volume: 4 Issue: 2 Year: 2006 Page: 133-144
Author(s): G. P. Margison, A. C. Povey, M. Santibanez-Koref

Strategies to Improve the Killing of Tumors Using Temozolomide: Targeting the DNA Repair Protein MGMT

Journal: Current Medicinal Chemistry
Volume: 19 Issue: 2 Year: 2012 Page: 3886-3892
Author(s): G. Jiang, L. -T. Li, Y. Xin, L. Zhang, Y. -Q. Liu, J. -N. Zheng

Posttranslational Regulation of O6-Methylguanine-DNA Methyltransferase (MGMT) and New Opportunities for Treatment of Brain Cancers

Journal: Mini-Reviews in Medicinal Chemistry
Volume: 16 Issue: 6 Year: 2016 Page: 455-464
Author(s): Kalkunte S. Srivenugopal, Amit Rawat, Suryakant K. Niture, Ameya Paranjpe, Chinavenmani Velu, Sanjay N. Venugopal, Hanumantha Rao Madala, Debasish Basak, Surendra R. Punganuru

Role of Mismatch Repair and MGMT in Response to Anticancer Therapies

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 8 Issue: 4 Year: 2008 Page: 368-380
Author(s): Ida Casorelli, Maria Teresa Russo, Margherita Bignami

Research Article

O-6-methylguanine-DNA Methyltransferase Inhibits Gastric Carcinoma Cell Migration and Invasion by Downregulation of Matrix Metalloproteinase 2

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 16 Issue: 9 Year: 2016 Page: 1125-1132
Author(s): Chenglong Li,Li Deng,Hugang Shen,Qingyou Meng,Aimin Qian,Hongfei Sang,Jiazeng Xia,Xiaoqiang Li

Research Article

Effect of O6-Substituted Guanine Analogs on O6-methylguanine DNA-methyltransferase Expression and Glioblastoma Cells Viability

Journal: Medicinal Chemistry
Volume: 13 Issue: 1 Year: 2017 Page: 28-39
Author(s): Patrick-Denis St-Coeur, Marc Cormier, Veronique C. LeBlanc, Pier Jr. Morin, Mohamed Touaibia

Review Article

Current Therapeutic Alternatives and New Perspectives in Glioblastoma Multiforme

Journal: Current Medicinal Chemistry
Volume: 24 Issue: 25 Year: 2017 Page: 2781-2795
Author(s): Ángelo S.T. Arévalo,José I. Erices,Daniel A. Uribe,Jake Howden,Ignacio Niechi,Sebastián Muñoz,Rody S. Martín,Claudia A.Q. Monrás

Targeted Therapy for Brain Tumours: Role of PARP Inhibitors

Journal: Current Cancer Drug Targets
Volume: 12 Issue: 3 Year: 2012 Page: 218-236
Author(s): C. Leonetti, A. Biroccio, G. Graziani, L. Tentori

The Role of Integrins in Glioma Biology and Anti-Glioma Therapies

Journal: Current Pharmaceutical Design
Volume: 17 Issue: 2 Year: 2011 Page: 2402-2410
Author(s): Ghazaleh Tabatabai, Jorg-Christian Tonn, Roger Stupp, Michael Weller

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