Search Result "MDM2 E3 ligase inhibitory activity"


Reactivation of p53 by Inhibiting Mdm2 E3 Ligase: A Novel Antitumor Approach

Journal: Current Cancer Drug Targets
Volume: 11 Issue: 8 Year: 2011 Page: 987-994
Author(s): J. Di, Y. Zhang, J. Zheng

Escape, or Vanish: Control the Fate of p53 through MDM2-Mediated Ubiquitination

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 16 Issue: 2 Year: 2016 Page: 174-189
Author(s): Jinlian Wei,Yingrui Yang,Mengchen Lu,Lili Xu,Fang Liu,Zhenwei Yuan,Qichao Bao,Zhengyu Jiang,Xiaoli Xu,Xiaoke Guo,Xiaojin Zhang,Qidong You,Haopeng Sun

Synthesis and Biological Evaluation of Novel Pyrimido[4,5-b]quinoline-2,4- dione Derivatives as MDM2 Ubiquitin Ligase Inhibitors

Journal: Medicinal Chemistry
Volume: 9 Issue: 4 Year: 2013 Page: 581-587
Author(s): Xiaoxue Dou, Xin Li, Liu Tao, Chunqi Hu, Lei Zhang, Qiaojun He, Bo Yang, Yongzhou Hu

SCF E3 Ubiquitin Ligases as Anticancer Targets

Journal: Current Cancer Drug Targets
Volume: 11 Issue: 3 Year: 2011 Page: 347-356
Author(s): L. Jia, Y. Sun

RING-, HECT-, and RBR-type E3 Ubiquitin Ligases: Involvement in Human Cancer

Journal: Current Cancer Drug Targets
Volume: 16 Issue: 2 Year: 2016 Page: 157-174
Author(s): Chiharu Uchida,Masatoshi Kitagawa

RING Finger E3 Ubiquitin Ligases: Structure and Drug Discovery

Journal: Current Pharmaceutical Design
Volume: 15 Issue: 3 Year: 2009 Page: 3716-3731
Author(s): Christos T. Chasapis, Georgios A. Spyroulias

Review Article

Recent Advancements in the Discovery of MDM2/MDM2-p53 InteractionInhibitors for the Treatment of Cancer

Journal: Current Medicinal Chemistry
Volume: 30 Issue: 32 Year: 2023 Page: 3668-3701
Author(s):

Cullin-RING Ligases as Attractive Anti-cancer Targets

Journal: Current Pharmaceutical Design
Volume: 19 Issue: 1 Year: 2013 Page: 3215-3225
Author(s): Yongchao Zhao, Yi Sun

Pharmacologic Activation of p53 by Small-Molecule MDM2 Antagonists

Journal: Current Pharmaceutical Design
Volume: 17 Issue: 6 Year: 2011 Page: 560-568
Author(s): Hong Shen, Carl G. Maki

Recent Advances in Validating MDM2 as a Cancer Target

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 9 Issue: 8 Year: 2009 Page: 882-903
Author(s): Elizabeth R. Rayburn, Scharri J. Ezell, Ruiwen Zhang

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