Search Result "IL-6 trans-signaling"


Appreciating the Balance between Classical Interleukin (IL)-6 Receptor Signaling and IL-6 Trans-Signaling: Implications for Arthritis Progression

Journal: Immunology, Endocrine & Metabolic Agents in Medicinal Chemistry
Volume: 8 Issue: 3 Year: 2008 Page: 235-246
Author(s): Simon A. Jones, Gareth W. Jones, Anwen S. Williams, Mari A. Nowell

Signaling Molecules: The Pathogenic Role of the IL-6/STAT-3 Trans Signaling Pathway in Intestinal Inflammation and in Colonic Cancer

Journal: Current Drug Targets
Volume: 9 Issue: 5 Year: 2008 Page: 369-374
Author(s): R. Atreya, M. F. Neurath

Roles of IL-6-gp130 Signaling in Vascular Inflammation

Journal: Current Cardiology Reviews
Volume: 4 Issue: 3 Year: 2008 Page: 179-192
Author(s): Tieying Hou, Brian C. Tieu, Sutapa Ray, Adrian Recinos III, Ruwen Cui, Ronald G. Tilton, Allan R. Brasier

Prevention of Colitis-associated Cancer: Natural Compounds that Target the IL-6 Soluble Receptor

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 12 Issue: 10 Year: 2012 Page: 1221-1238
Author(s): Cate Moriasi,Dharmalingam Subramaniam,Shanjana Awasthi,Satish Ramalingam,Shrikant Anant

Interleukin-6 Trans-Signaling and Colonic Cancer Associated with Inflammatory Bowel Disease

Journal: Current Pharmaceutical Design
Volume: 15 Issue: 1 Year: 2009 Page: 2095-2103
Author(s): Stefan Rose-John, Keiichi Mitsuyama, Satoshi Matsumoto, Wolfgang M. Thaiss, Jurgen Scheller

Targeting the IL-6 Pathway in Multiple Myeloma and its Implications in Cancer-Associated Gene Hypermethylation

Journal: Medicinal Chemistry
Volume: 7 Issue: 5 Year: 2011 Page: 473-479
Author(s): Susan Blaydes Ingersoll, Sarfraz Ahmad, Natalie D. Thoni, Farhana H. Ahmed, Kimberly A. Monahan, John R. Edwards

IL-6 Signaling and its Blockade with a Humanized Anti-Interleukin-6 Receptor Antibody in Rheumatoid Arthritis: Advent of a New and Innovative Therapeutic Drug, Tocilizumab

Journal: Current Rheumatology Reviews
Volume: 7 Issue: 4 Year: 2011 Page: 288-300
Author(s): Yoshiyuki Ohsugi, Tadamitsu Kishimoto

Review Article

Immunotherapeutic Interleukin-6 or Interleukin-6 Receptor Blockade in Cancer: Challenges and Opportunities

Journal: Current Medicinal Chemistry
Volume: 25 Issue: 36 Year: 2018 Page: 4785-4806
Author(s): Nirmala Chandralega Kampan,Sue D. Xiang,Orla M. McNally,Andrew N. Stephens,Michael A. Quinn,Magdalena Plebanski

Interleukin-6: A Critical Cytokine in Cancer Multidrug Resistance

Journal: Current Pharmaceutical Design
Volume: 22 Issue: 5 Year: 2016 Page: 518-526
Author(s): Morteza Ghandadi, Amirhossein Sahebkar

IL-6 Activated JAK/STAT3 Pathway and Sensitivity to Hsp90 Inhibitors in Multiple Myeloma

Journal: Current Medicinal Chemistry
Volume: 21 Issue: 26 Year: 2014 Page: 3042-3047
Author(s): I. Kolosenko,D. Grander,K.P. Tamm

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