Search Result "HIT"


Review Article

Oral Factor Xa (FXa) Inhibitors for Treatment of Heparin-induced Thrombocytopenia (HIT)

Journal: Current Drug Therapy
Volume: 16 Issue: 2 Year: 2021 Page: 126-132
Author(s): Nicholas Munafo,Sagar Patel,Kristine C. Willett,Amanda Morrill

Trends in Hit-to-Lead: An Update

Ebook: Frontiers in Medicinal Chemistry
Volume: 3 Year: 2006
Author(s):
Doi: 10.2174/978160805206610603010653

Efficient Optimization Strategy for Marginal Hits Active Against abl Tyrosine Kinases

Journal: Current Drug Discovery Technologies
Volume: 1 Issue: 3 Year: 2004 Page: 201-210
Author(s): Sergey E. Tkachenko, Ilya Okun, Konstantin V. Balakin, Charles E. Petersen, Yan A. Ivanenkov, Nikolay P. Savchuk, Andrey A. Ivashchenko

Enzyme Kinetics and Hit Validation in Fluorimetric Protease Assays

Journal: Current Topics in Medicinal Chemistry
Volume: 10 Issue: 3 Year: 2010 Page: 368-382
Author(s): Stephanie Ludewig, Markus Kossner, Markus Schiller, Knut Baumann, Tanja Schirmeister

Novel, Acidic CCR2 Receptor Antagonists: From Hit to Lead

Journal: Letters in Drug Design & Discovery
Volume: 4 Issue: 3 Year: 2007 Page: 185-191
Author(s): D. Zou, H.-X. Zhai, J. Eckman, P. Higgins, M. Gillard, L. Knerr, S. Carre, P. Pasau, P. Collart, J. Grassi

Lead Generation - Enhancing the Success of Drug Discovery by Investing in the Hit to Lead Process

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 6 Issue: 1 Year: 2003 Page: 51-66
Author(s): Alexander Alanine, Matthias Nettekoven, Edward Roberts, Andrew W. Thomas

NMR Screening and Hit Validation in Fragment Based Drug Discovery

Journal: Current Topics in Medicinal Chemistry
Volume: 11 Issue: 1 Year: 2011 Page: 43-67
Author(s): Ramon Campos-Olivas

Increasing the Odds of Drug Hit Identification by Screening Against Receptor Homologs?

Journal: Letters in Drug Design & Discovery
Volume: 3 Issue: 3 Year: 2006 Page: 200-204
Author(s): Z. L. Ji, Z. R. Li, J. F. Wang, C. Z. Cai, L. Y. Han, C. J. Zheng, Y. Z. Chen

Research Article

Discovery of Ten Anti-HIV Hit Compounds and PreliminaryPharmacological Mechanisms Studies

Journal: Current HIV Research
Volume: 22 Issue: 2 Year: 2024 Page: 82-90
Author(s):

A Collaborative Hit-to-Lead Investigation Leveraging Medicinal Chemistry Expertise with High Throughput Library Design, Synthesis and Purification Capabilities

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 9 Issue: 2 Year: 2006 Page: 123-130
Author(s): X. Yang, D. Parker, L. Whitehead, N. S. Ryder, B. Weidmann, M. Stabile-Harris, D. Kizer, M. McKinnon, A. Smellie, D. Powers

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