Search Result "GPCR. SAR"


Targeting Platelet G-Protein Coupled Receptors (GPCRs): Looking Beyond Conventional GPCR Antagonism

Journal: Current Vascular Pharmacology
Volume: 8 Issue: 2 Year: 2010 Page: 140-154
Author(s): Louisa Dowal, Robert Flaumenhaft

G-Protein Coupled Receptors (GPCRs): A Comprehensive Computational Perspective

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 18 Issue: 4 Year: 2015 Page: 346-364
Author(s): M. Ramesh, Mahmoud E. Soliman

The Therapeutic Potential of Allosteric Ligands for Free Fatty Acid Sensitive GPCRs

Journal: Current Topics in Medicinal Chemistry
Volume: 13 Issue: 1 Year: 2013 Page: 14-25
Author(s): Brian D. Hudson, Trond Ulven, Graeme Milligan

Structure-Based Design in the GPCR Target Space

Journal: Current Medicinal Chemistry
Volume: 19 Issue: 4 Year: 2012 Page: 544-556
Author(s): M. Kontoyianni, Z. Liu

Review Article

Potential for the Rational Design of Allosteric Modulators of Class C GPCRs

Journal: Current Topics in Medicinal Chemistry
Volume: 17 Issue: 1 Year: 2017 Page: 71-78
Author(s): John A. Christopher,Andrew S. Doré,Benjamin G. Tehan

The Family B1 GPCR: Structural Aspects and Interaction with Accessory Proteins

Journal: Current Drug Targets
Volume: 13 Issue: 1 Year: 2012 Page: 103-115
Author(s): Alain Couvineau, Marc Laburthe

Thematic Analysis™ : A Chemogenomic Approach to GPCR Drug Discovery

Journal: Current Topics in Medicinal Chemistry
Volume: 11 Issue: 1 Year: 2011 Page: 1925-1943
Author(s): Roger Crossley, Jacqueline Anne Macritchie, Martin John Slater

The Selection and Design of GPCR Ligands: From Concept to the Clinic

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 7 Issue: 5 Year: 2004 Page: 441-452
Author(s): Mark Ashton, Michael H. Charlton, Matthias K. Schwarz, Russell J. Thomas, Mark Whittaker

Drug Design of GPCR Ligands Using Physicogenetics and Chemogenomics - Principles and Case Studies

Journal: Current Topics in Medicinal Chemistry
Volume: 11 Issue: 1 Year: 2011 Page: 1882-1901
Author(s): Thomas M. Frimurer, Thomas Hogberg

Discovery of GPCR Ligands by Molecular Docking Screening: Novel Opportunities Provided by Crystal Structures

Journal: Current Topics in Medicinal Chemistry
Volume: 15 Issue: 24 Year: 2015 Page: 2484-2503
Author(s): David Rodríguez,Anirudh Ranganathan,Jens Carlsson

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