Search Result "GGTase-I"


Theoretical Studies on Binding and Specificity Mechanisms of Farnesyltransferase (FTase) and Geranylgeranyltransferase Type-I (GGTase-I) Inhibitors by Molecular Modeling

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 17 Issue: 6 Year: 2014 Page: 509-519
Author(s): Shirou Zhou

Research Article

Protein Geranylgeranyltransferase Type 1 as a Target in Cancer

Journal: Current Cancer Drug Targets
Volume: 16 Issue: 7 Year: 2016 Page: 563-571
Author(s): Nisar Ullah, Muhammad Mansha, Patrick J. Casey

Modulation of k-Ras Signaling by Natural Products

Journal: Current Medicinal Chemistry
Volume: 19 Issue: 14 Year: 2012 Page: 2273-2291
Author(s): S.B. Bharate, B. Singh, R.A. Vishwakarma

Targeting the RAS Signaling Pathway in Malignant Hematologic Diseases

Journal: Current Drug Targets
Volume: 8 Issue: 2 Year: 2007 Page: 217-235
Author(s): M. A. Morgan, A. Ganser, C. W. M. Reuter

Exploring Structure-Activity Relationships of Tricyclic Farnesyltransferase Inhibitors Using ECLiPS® Libraries

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 9 Issue: 7 Year: 2006 Page: 545-558
Author(s): Laura L. Rokosz, Chia-Yu Huang, John C. Reader, Tara M. Stauffer, Eileen C. Southwick, Ge Li, Daniel Chelsky, John J. Baldwin

Inhibitors of Chronically Active Ras: Potential for Treatment of Human Malignancies

Journal: Recent Patents on Anti-Cancer Drug Discovery
Volume: 3 Issue: 1 Year: 2008 Page: 31-47
Author(s): Yoel Kloog, Roy Blum, Adrienne D. Cox

Farnesyltransferase Inhibitors: A Detailed Chemical View on an Elusive Biological Problem

Journal: Current Medicinal Chemistry
Volume: 15 Issue: 1 Year: 2008 Page: 1478-1492
Author(s): Sergio F. Sousa, Pedro A. Fernandes, Maria Joao Ramos

Inhibitors of Protein: Geranylgeranyl Transferases

Ebook: Frontiers in Medicinal Chemistry
Volume: 5 Year: 2010
Author(s): Farid El Oualid, Gijs A. van der Marel, Mark Overhand
Doi: 10.2174/978160805208011005010167

Inhibitors of Protein: Geranylgeranyl Transferases

Journal: Current Medicinal Chemistry
Volume: 13 Issue: 2 Year: 2006 Page: 2385-2427
Author(s): Farid El Oualid, Louis H. Cohen, Gijs A. van der Marel, Mark Overhand

Variously Substituted (Phosphonoacetamido)Oxy Analogues of Geranylgeranyl Diphosphate (GGdP) as GGdP-transferase (GGTase) Inhibitors and Antiproliferative Agents

Journal: Medicinal Chemistry
Volume: 1 Issue: 3 Year: 2005 Page: 239-244
Author(s): Filippo Minutolo, Valentina Asso, Simone Bertini, Laura Betti, Massimiliano Ciriaco, Romano Danesi, Gianbattista Gervasi, Elisa Ghilardi, Elisa Giovanetti, Gino Giannaccini

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