Search Result "GGTI"


Research Article

Protein Geranylgeranyltransferase Type 1 as a Target in Cancer

Journal: Current Cancer Drug Targets
Volume: 16 Issue: 7 Year: 2016 Page: 563-571
Author(s): Nisar Ullah, Muhammad Mansha, Patrick J. Casey

Theoretical Studies on Binding and Specificity Mechanisms of Farnesyltransferase (FTase) and Geranylgeranyltransferase Type-I (GGTase-I) Inhibitors by Molecular Modeling

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 17 Issue: 6 Year: 2014 Page: 509-519
Author(s): Shirou Zhou

Inhibitors of Chronically Active Ras: Potential for Treatment of Human Malignancies

Journal: Recent Patents on Anti-Cancer Drug Discovery
Volume: 3 Issue: 1 Year: 2008 Page: 31-47
Author(s): Yoel Kloog, Roy Blum, Adrienne D. Cox

Effect of HMG-CoA Reductase Inhibition on Vascular Smooth Muscle Cells Extracellular Matrix Production: Role of RhoA

Journal: Current Vascular Pharmacology
Volume: 14 Issue: 4 Year: 2016 Page: 345-352
Author(s): Rogelio Palomino-Morales, Sonia Perales, Carolina Torres, Ana Linares, Maria J. Alejandre

Rho GTPases: Promising Cellular Targets for Novel Anticancer Drugs

Journal: Current Cancer Drug Targets
Volume: 6 Issue: 1 Year: 2006 Page: 1-14
Author(s): Gerhard Fritz, Bernd Kaina

Targeting the Mevalonate Pathway for Improved Anticancer Therapy

Journal: Current Cancer Drug Targets
Volume: 9 Issue: 5 Year: 2009 Page: 626-638
Author(s): G. Fritz

Targeting the RAS Signaling Pathway in Malignant Hematologic Diseases

Journal: Current Drug Targets
Volume: 8 Issue: 2 Year: 2007 Page: 217-235
Author(s): M. A. Morgan, A. Ganser, C. W. M. Reuter

Mevalonate-Ras Homology (Rho)/Rho-Associated Coiled-Coil-Forming Protein Kinase (ROCK)-Mediated Signaling Pathway as a Therapeutic Target for the Treatment of Endometriosis-Associated Fibrosis

Journal: Current Signal Transduction Therapy
Volume: 5 Issue: 2 Year: 2010 Page: 141-148
Author(s): Kaei Nasu, Akitoshi Tsuno, Akitoshi Yuge, Hisashi Narahara

Atorvastatin Inhibits Advanced Glycation End Products (AGE)-Induced C-Reactive Expression in Hepatoma Cells by Suppressing Reactive Oxygen Species Generation

Journal: Vascular Disease Prevention
Volume: 4 Issue: 3 Year: 2007 Page: 213-216
Author(s): Takafumi Yoshida, Sho-ichi Yamagishi, Kazuo Nakamura, Takanori Matsui, Tsutomu Imaizumi, Masayoshi Takeuchi, Teruhiko Makino, Tadamichi Shimizu, Michio Sata

The Molecular Mechanisms of TRAIL Resistance in Cancer Cells: Help in Designing New Drugs

Journal: Current Pharmaceutical Design
Volume: 20 Issue: 42 Year: 2014 Page: 6714-6722
Author(s): Feng Wang,Junsheng Lin,Ruian Xu

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