Search Result "FXR antagonists"


Research Article

Medicinal Chemistry and Pharmacological Effects of Farnesoid X Receptor (FXR) Antagonists

Journal: Current Topics in Medicinal Chemistry
Volume: 14 Issue: 19 Year: 2014 Page: 2188-2205
Author(s): Christina Lamers,Manfred Schubert-Zsilavecz,Daniel Merk

Recent Advances in Non-Steroidal FXR Antagonists Development for Therapeutic Applications

Journal: Current Topics in Medicinal Chemistry
Volume: 14 Issue: 19 Year: 2014 Page: 2175-2187
Author(s): Huang Huang,Yong Xu,Jin Zhu,Jian Li

Development of FXR, PXR and CAR Agonists and Antagonists for Treatment of Liver Disorders

Journal: Current Topics in Medicinal Chemistry
Volume: 12 Issue: 6 Year: 2012 Page: 605-624
Author(s): Stefano Fiorucci, Angela Zampella, Eleonora Distrutti

Research Article

Synthesis and Biological Evaluation of N-(5-(2,5-dimethyl-phenoxy)-2,2-dimethylpentyl)-benzamide Derivatives as Novel Farnesoid X Receptor (FXR) Antagonist

Journal: Letters in Drug Design & Discovery
Volume: 15 Issue: 9 Year: 2018 Page: 923-936
Author(s): Siyun Nian,Zhenpeng Yu,Xiangduan Tan,Xia Gan,Mohan Huang,Yihuan Zhou,Guoping Wang

FXR, A Therapeutic Target for Bile Acid and Lipid Disorders

Journal: Mini-Reviews in Medicinal Chemistry
Volume: 5 Issue: 8 Year: 2005 Page: 719-727
Author(s): Stefan Westin, Richard A. Heyman, Richard Martin

Review Article

Farnesoid-X Receptor (FXR) as a Promising Pharmaceutical Target in Atherosclerosis

Journal: Current Medicinal Chemistry
Volume: 24 Issue: 1 Year: 2017 Page: 1147-1157
Author(s): Demetrios Moris,Constantinos Giaginis,Gerasimos Tsourouflis,Stamatios Theocharis

Role of FXR in Regulating Bile Acid Homeostasis and Relevance for Human Diseases

Journal: Current Drug Targets - Immune, Endocrine & Metabolic Disorders
Volume: 5 Issue: 3 Year: 2005 Page: 289-303
Author(s): G. Rizzo, B. Renga, A. Mencarelli, R. Pellicciari, S. Fiorucci

Beyond Bile Acids: Targeting Farnesoid X Receptor (FXR) with Natural and Synthetic Ligands

Journal: Current Topics in Medicinal Chemistry
Volume: 14 Issue: 19 Year: 2014 Page: 2129-2142
Author(s): Andrea Carotti,Maura Marinozzi,Chiara Custodi,Bruno Cerra,Roberto Pellicciari,Antimo Gioiello,Antonio Macchiarulo

Bile Acids and Derivatives, Their Nuclear Receptors FXR, PXR and Ligands: Role in Health and Disease and Their Therapeutic Potential

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 8 Issue: 5 Year: 2008 Page: 540-563
Author(s): Amazia Zimber, Christian Gespach

Hologram QSAR Studies on Farnesoid X Receptor Activators

Journal: Letters in Drug Design & Discovery
Volume: 3 Issue: 4 Year: 2006 Page: 261-267
Author(s): Kathia M. Honorio, Richard C. Garratt, Igor Polikarpov, Adriano D. Andricopulo

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