Search Result "DXR"


Targeting the Methyl Erythritol Phosphate (MEP) Pathway for Novel Antimalarial, Antibacterial and Herbicidal Drug Discovery: Inhibition of 1-Deoxy-D-Xylulose-5-Phosphate Reductoisomerase (DXR) Enzyme

Journal: Current Pharmaceutical Design
Volume: 13 Issue: 1 Year: 2007 Page: 1161-1177
Author(s): Nidhi Singh, Gweneal Cheve, Mitchell A. Avery, Christopher R. McCurdy

Inhibition Studies on Enzymes Involved in Isoprenoid Biosynthesis. Focus on Two Potential Drug Targets: DXR and IDI-2 Enzymes

Journal: Current Enzyme Inhibition
Volume: 7 Issue: 2 Year: 2011 Page: 79-95
Author(s): Jerome de Ruyck, Johan Wouters, C. Dale Poulter

Inhibition of 1-Deoxy-D-Xylulose-5-Phosphate Reductoisomerase (Dxr): A Review of the Synthesis and Biological Evaluation of Recent Inhibitors

Journal: Current Topics in Medicinal Chemistry
Volume: 12 Issue: 7 Year: 2012 Page: 706-728
Author(s): Emily R. Jackson,Cynthia S. Dowd

Bone-Targeted Doxorubicin-Loaded Nanoparticles as a Tool for the Treatment of Skeletal Metastases

Journal: Current Cancer Drug Targets
Volume: 10 Issue: 7 Year: 2010 Page: 649-659
Author(s): M. Salerno, E. Cenni, C. Fotia, S. Avnet, D. Granchi, F. Castelli, D. Micieli, R. Pignatello, M. Capulli, N. Rucci, A. Angelucci, A. Del Fattore, A. Teti, N. Zini, A. Giunti, N. Baldini

The Malarial Drug Target Plasmodium falciparum 1-Deoxy-D-Xylulose-5- Phosphate Reductoisomerase (PfDXR): Development of a 3-D Model for Identification of Novel, Structural and Functional Features and for Inhibitor Screening (Supplementary Information)

Journal: Protein & Peptide Letters
Volume: 17 Issue: 1 Year: 2010 Page: 109-120
Author(s): Jessica L. Goble, Matthew R. Adendorff, Tjaart A.P. de Beer, Linda L. Stephens, Gregory L. Blatch

The Druggable Antimalarial Target PfDXR: Overproduction Strategies and Kinetic Characterization

Journal: Protein & Peptide Letters
Volume: 20 Issue: 2 Year: 2013 Page: 115-124
Author(s): Jessica L. Goble,Hailey Johnson,Jaco de Ridder,Linda L. Stephens,Abraham Louw,Gregory L. Blatch,Aileen Boshoff

Research Article

Development of Long-Circulating and Fusogenic Liposomes Coencapsulating Paclitaxel and Doxorubicin in Synergistic Ratio for the Treatment of Breast Cancer

Journal: Current Drug Delivery
Volume: 16 Issue: 9 Year: 2019 Page: 829-838
Author(s): Marjorie Coimbra Roque,Marina Santiago Franco,José Mário Carneiro Vilela,Margareth Spangler Andrade,André Luís Branco de Barros,Elaine Amaral Leite,Mônica Cristina Oliveira

Acridine Orange is an Effective Anti-Cancer Drug that Affects Mitochondrial Function in Osteosarcoma Cells

Journal: Current Pharmaceutical Design
Volume: 21 Issue: 28 Year: 2015 Page: 4088-4094
Author(s): Caterina Fotia,Sofia Avnet,Katsuyuki Kusuzaki,Laura Roncuzzi,Nicola Baldini

β-Cyclodextrin Conjugates with Glucose Moieties Designed as Drug Carriers: Their Syntheses, Evaluations Using Concanavalin A and Doxorubicin, and Structural Analyses by NMR Spectroscopy

Journal: Medicinal Chemistry
Volume: 4 Issue: 3 Year: 2008 Page: 244-255
Author(s): Yoshiki Oda, Natsumi Kobayashi, Takashi Yamanoi, Kaname Katsuraya, Keiko Takahashi, Kenjiro Hattori

Preparation of a Cyclodextrin Conjugated With Two Arbutin Moieties as a Drug-Carrier Model, and its High Ability for the Inclusion of Doxorubicin

Journal: Letters in Drug Design & Discovery
Volume: 3 Issue: 3 Year: 2006 Page: 188-191
Author(s): Takashi Yamanoi, Natsumi Kobayashi, Keiko Takahashi, Kenjiro Hattori

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