Search Result "DDI with CYP 3A4 substrates"


Modulation of Cytochrome-P450 Inhibition (CYP) in Drug Discovery: A Medicinal Chemistry Perspective

Journal: Current Medicinal Chemistry
Volume: 19 Issue: 21 Year: 2012 Page: 3605-3621
Author(s): Sanjay Kumar,Rajiv Sharma,Abhijit Roychowdhury

CYP Inhibition-Mediated Drug-Drug Interactions

Journal: Current Enzyme Inhibition
Volume: 6 Issue: 3 Year: 2010 Page: 130-145
Author(s): Karoly Tihanyi, Monika L. Bakk, Eva Hellinger, Monika Vastag

Enzyme Kinetics for Clinically Relevant CYP Inhibition

Journal: Current Drug Metabolism
Volume: 6 Issue: 3 Year: 2005 Page: 241-257
Author(s): Zhi-Yi Zhang, Y. Nancy Wong

The Use of HepaRG and Human Hepatocyte Data in Predicting CYP Induction Drug-Drug Interactions via Static Equation and Dynamic Mechanistic Modelling Approaches

Journal: Current Drug Metabolism
Volume: 11 Issue: 1 Year: 2010 Page: 870-885
Author(s): Ken Grime, Douglas D. Ferguson, Robert J. Riley

Research Article

Drug-Drug Interaction Potential of Remimazolam: CYP 450, Transporters, and Protein Binding

Journal: Current Drug Metabolism
Volume: 25 Issue: 4 Year: 2024 Page: 266-275
Author(s):

Inhibition of Major Drug Metabolizing CYPs by Common Herbal Medicines used by HIV/AIDS Patients in Africa– Implications for Herb- Drug Interactions

Journal: Drug Metabolism Letters
Volume: 7 Issue: 2 Year: 2013 Page: 83-95
Author(s): Charles Awortwe,Patrick J. Bouic,Collen M. Masimirembwa,Bernd Rosenkranz

Assessment of Cytochrome P450 Enzyme Inhibition and Inactivation in Drug Discovery and Development

Journal: Current Topics in Medicinal Chemistry
Volume: 11 Issue: 4 Year: 2011 Page: 382-403
Author(s): David O. Nettleton, Heidi J. Einolf

High-Throughput, 384-Well, LC-MS/MS CYP Inhibition Assay Using Automation, Cassette-Analysis Technique and Streamlined Data Analysis

Journal: Drug Metabolism Letters
Volume: 5 Issue: 3 Year: 2011 Page: 220-230
Author(s): Jason S. Halladay, Erlie Marie Delarosa, Daniel Tran, Leslie Wang, Susan Wong, S. Cyrus Khojasteh

Research Article

ZY12201: A Potent TGR5 Agonist: Identification of a Novel Pan CYP450Inhibitor Tool Compound for In-Vitro Assessment

Journal: Drug Metabolism and Bioanalysis Letters
Volume: 15 Issue: 2 Year: 2022 Page: 116-132
Author(s):

Quantitative Evaluation of Drug-Drug Interaction Potentials by in vivo Information- Guided Prediction Approach

Journal: Current Drug Metabolism
Volume: 15 Issue: 8 Year: 2014 Page: 761-766
Author(s): Feng Chen,Zhe-Yi Hu,Wei-Wei Jia,Jing-Tao Lu,Yuan-Sheng Zhao

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