Search Result "Common Hits Approach."


Rational Design Approaches to Chemical Libraries for Hit Identification

Journal: Current Drug Discovery Technologies
Volume: 3 Issue: 1 Year: 2006 Page: 49-65
Author(s): Konstantin V. Balakin, Alexander V. Kozintsev, Alex S. Kiselyov, Nikolay P. Savchuk

NMR Screening and Hit Validation in Fragment Based Drug Discovery

Journal: Current Topics in Medicinal Chemistry
Volume: 11 Issue: 1 Year: 2011 Page: 43-67
Author(s): Ramon Campos-Olivas

Enzyme Kinetics and Hit Validation in Fluorimetric Protease Assays

Journal: Current Topics in Medicinal Chemistry
Volume: 10 Issue: 3 Year: 2010 Page: 368-382
Author(s): Stephanie Ludewig, Markus Kossner, Markus Schiller, Knut Baumann, Tanja Schirmeister

Synergies of Virtual Screening Approaches

Journal: Mini-Reviews in Medicinal Chemistry
Volume: 8 Issue: 9 Year: 2008 Page: 927-933
Author(s): Ingo Muegge

Integrity Profiling of High Throughput Screening Hits Using LC-MS and Related Techniques

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 8 Issue: 6 Year: 2005 Page: 459-466
Author(s): Edward H. Kerns, Li Di, Jim Bourassa, Jonathan Gross, Nelson Huang, Hanlan Liu, Teresa Kleintop, Lisa Nogle, Larry Mallis, Chris Petucci, Susan Petusky, Mark Tischler, Chantel Sabus, Ani Sarkahian, Mairead Young, Mei-yi Zhang, Donna Huryn, Oliver McConnell, Guy Carter

Finding New Hits in Neglected Disease Projects: Target or Phenotypic Based Screening?

Journal: Current Topics in Medicinal Chemistry
Volume: 11 Issue: 1 Year: 2011 Page: 1284-1291
Author(s): Ian H. Gilbert, Didier Leroy, Julie A. Frearson

A Simple Method for Analyzing Actives in Random RNAi Screens: Introducing the “H Score” for Hit Nomination & Gene Prioritization

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 15 Issue: 9 Year: 2012 Page: 686-704
Author(s): Bhavneet Bhinder,Hakim Djaballah

Hit Triage Using Efficiency Indices after Screening of Compound Libraries in Drug Discovery

Journal: Current Topics in Medicinal Chemistry
Volume: 9 Issue: 1 Year: 2009 Page: 1718-1724
Author(s): Allen B. Reitz, Garry R. Smith, Brett A. Tounge, Charles H. Reynolds

Systematic Analysis of RNAi Reports Identifies Dismal Commonality at Gene-Level and Reveals an Unprecedented Enrichment in Pooled shRNA Screens

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 16 Issue: 9 Year: 2013 Page: 665-681
Author(s): Bhavneet Bhinder, Hakim Djaballah

The Identification, Characterization and Optimization of Small Molecule Probes of Cysteine Proteases: Experiences of the Penn Center for Molecular Discovery with Cathepsin B and Cathepsin L

Journal: Current Topics in Medicinal Chemistry
Volume: 9 Issue: 1 Year: 2009 Page: 1206-1216
Author(s): Donna M. Huryn, Amos B. Smith III

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