Search Result "CYP2C"


The Transcriptional Regulation of the Human CYP2C Genes

Journal: Current Drug Metabolism
Volume: 10 Issue: 6 Year: 2009 Page: 567-578
Author(s): Yuping Chen, Joyce A. Goldstein

Research Article

CYP2C and CYP2B Mediated Metabolic Activation of Retrorsine in Cyp3a Knockout Mice

Journal: Current Drug Metabolism
Volume: 21 Issue: 13 Year: 2020 Page: 1040-1051
Author(s): Xiaoyan Pang,Chongzhuang Tang,Fandi Kong,Meixia Chen,Xiaoyan Chen

Comparison of Cytochrome P450 2C Subfamily Members in Terms of Drug Oxidation Rates and Substrate Inhibition

Journal: Current Drug Metabolism
Volume: 13 Issue: 8 Year: 2012 Page: 1145-1159
Author(s): Toshiro Niwa, Hiroshi Yamazaki

A Non-acidic Sulfaphenazole Analog Demonstrating High Intrinsic Clearance and Selectivity by Canine CYP2C21

Journal: Drug Metabolism Letters
Volume: 5 Issue: 4 Year: 2011 Page: 253-258
Author(s): Charles W. Locuson, Josh F. Alfaro, Matthew J. Zaya, Denis Billen, Julie A. White, Jeffrey P. Jones

Application of Pharmacogenomics in Drug Discovery and Development:Correlations Between Transcriptional Modulation and Preclinical Safety Observations

Journal: Drug Metabolism Letters
Volume: 1 Issue: 1 Year: 2007 Page: 41-48
Author(s): Lilian G. Yengi, Qian Xiang, Li Shen, Appavu Chandrasekaran, John Kao, JoAnn Scatina

Comparison of Enzyme Kinetic Parameters Obtained In Vitro for Reactions Mediated by Human CYP2C Enzymes Including Major CYP2C9 Variants

Journal: Current Drug Metabolism
Volume: 11 Issue: 2 Year: 2010 Page: 153-161
Author(s): D. Rokitta, U. Fuhr

Investigating Human P450s Involved in Drug Metabolism via Homology with High-Resolution P450 Crystal Structures of the CYP2C Subfamily

Journal: Current Drug Metabolism
Volume: 7 Issue: 6 Year: 2006 Page: 589-598
Author(s): David F.V. Lewis, Yuko Ito, Peter S. Goldfarb

The Roles of Cytochrome P450 in Ischemic Heart Disease

Journal: Current Drug Metabolism
Volume: 12 Issue: 6 Year: 2011 Page: 526-532
Author(s): Motohiko Sato, Utako Yokoyama, Takayuki Fujita, Satoshi Okumura, Yoshihioro Ishikawa

Pharmacogenomics of Cytochrome P450 Enzymes in Tumours

Journal: Current Pharmacogenomics
Volume: 2 Issue: 3 Year: 2004 Page: 243-254
Author(s): Diane Downie, Patrick H. Rooney, Morag C.E. McFadyen, Graeme I. Murray

Comparison of P450 Enzymes Between Cynomolgus Monkeys and Humans: P450 Identities, Protein Contents, Kinetic Parameters, and Potential for Inhibitory Profiles

Journal: Current Drug Metabolism
Volume: 14 Issue: 2 Year: 2013 Page: 239-252
Author(s): Chie Emoto,Noriaki Yoda,Yasuhiro Uno,Kazuhide Iwasaki,Ken Umehara,Eiji Kashiyama,Hiroshi Yamazaki

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