Search Result "CPT inhibitors"


Therapeutic Targeting of CPT-11 Induced Diarrhea: A Case for Prophylaxis

Journal: Current Drug Targets
Volume: 14 Issue: 7 Year: 2013 Page: 777-797
Author(s): Umang Swami, Sanjay Goel, Sridhar Mani

Pharmacology of Topoisomerase I Inhibitors Irinotecan (CPT-11) and Topotecan

Journal: Current Cancer Drug Targets
Volume: 2 Issue: 2 Year: 2002 Page: 103-123
Author(s): Ron H.J. Mathijssen, Walter J. Loos, Jaap Verweij, Alex Sparreboom

Research Article

Enzyme and Transporter Kinetics for CPT-11 (Irinotecan) and SN-38: An Insight on Tumor Tissue Compartment Pharmacokinetics Using PBPK

Journal: Recent Patents on Anti-Cancer Drug Discovery
Volume: 14 Issue: 2 Year: 2019 Page: 177-186
Author(s): Yingfang Fan,Najia Mansoor,Tasneem Ahmad,Zhuo X. Wu,Rafeeq A. Khan,Martin Czejka,Syed Sharib,Mansoor Ahmed,Zhe S. Chen,Dong H. Yang

Research Article

The Positive Synergism of CPT and MK-801 in Behavioral Tests and in Reduction of Environmental Stress and Redox Signaling Changes in Mice Cerebral Cortex

Journal: CNS & Neurological Disorders - Drug Targets
Volume: 16 Issue: 7 Year: 2017 Page: 837-845
Author(s): Mariola Herbet,Aleksandra Szopa,Sylwia Wosko,Anna Serefko,Magdalena Izdebska,Monika Gawronska-Grzywacz,Iwona Piatkowska-Chmiel,Martyna Janas,Renata Gieroba,Agnieszka Korga,Ewa Poleszak,Jaroslaw Dudka

Therapeutic Targeting of Melanoma Cells Using Neural Stem Cells Expressing Carboxylesterase, a CPT-11 Activating Enzyme

Journal: Current Stem Cell Research & Therapy
Volume: 5 Issue: 3 Year: 2010 Page: 273-276
Author(s): Margarita Gutova, Joseph Najbauer, Mike Y. Chen, Philip M. Potter, Seung U. Kim, Karen S. Aboody

Research Article

Synthesis of Dual Target CPT-Ala-Nor Conjugates and Their Biological Activity Evaluation

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 19 Issue: 4 Year: 2019 Page: 502-508
Author(s): Chang K. Zhao,Lang Xu,Xian H. Wang,Yu J. Bao,Yuhe Wang

Comparison of (+)- and (-)-Hemipalmitoylcarnitinium as Inhibitors of Hepatic Mitochondrial Carnitine Palmitoyltransferases in Diabetic Rats

Journal: Medicinal Chemistry
Volume: 1 Issue: 5 Year: 2005 Page: 445-453
Author(s): P. S. Savle, N. E. Neptune, Y. Yang, J. H. Rouden, B. L. Kite, E. W. Sugandhi, R. V. Macri, K. Kashfi, R. D. Gandour

Combination Therapy of Intraperitoneal Rapamycin and Convection- Enhanced Delivery of Nanoliposomal CPT-11 in Rodent Orthotopic Brain Tumor Xenografts

Journal: Current Cancer Drug Targets
Volume: 15 Issue: 4 Year: 2015 Page: 352-362
Author(s): Marina Mendiburu-Elicabe,Jon Gil-Ranedo

Review Article

Carboxylesterase Inhibitors: An Update

Journal: Current Medicinal Chemistry
Volume: 25 Issue: 14 Year: 2018 Page: 1627-1649
Author(s): Li-Wei Zou,Qiang Jin,Dan-Dan Wang,Qing-Kai Qian,Da-Cheng Hao,Guang-Bo Ge,Ling Yang

Pharmacokinetic Mechanisms for Reduced Toxicity of Irinotecan by Coadministered Thalidomide

Journal: Current Drug Metabolism
Volume: 7 Issue: 4 Year: 2006 Page: 431-454
Author(s): Xiao-Xia Yang, Ze-Ping Hu, Sui Y. Chan, Wei Duan, Paul C.-L. Ho, Urs A. Boelsterli, Ka-Yun Ng, Eli Chan, Jin-Song Bian, Yu-Zong Chen, Min Huang, > Zhou

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