Search Result "COX-1/COX-2 inhibition"


Clinical Implications of COX-1 and / or COX-2 Inhibition for the Distal Gastrointestinal Tract

Journal: Current Pharmaceutical Design
Volume: 9 Issue: 2 Year: 2003 Page: 2253-2266
Author(s): Angel Lanas, Julian Panes, Josep M. Pique

Research Article

Evaluation of the Effect of α-L-Guluronic Acid (G2013) on COX-1, COX-2 Activity and Gene Expression for Introducing this Drug as a Novel NSAID with Immunomodulatory Property

Journal: Recent Patents on Inflammation & Allergy Drug Discovery
Volume: 12 Issue: 2 Year: 2018 Page: 162-168
Author(s): Abbas Mirshafiey,Seyed S. Mortazavi-Jahromi,Mahsa Taeb,Salvatore Cuzzocrea,Emanuela Esposito

The Molecular Basis of COX-2 Versus COX-1 Selectivity of Lumiracoxib by Molecular Docking Studies

Journal: Letters in Drug Design & Discovery
Volume: 4 Issue: 6 Year: 2007 Page: 422-425
Author(s): Celia M. Correa, Andre F. de Paula, Gilberto M.S. da Silva, Carlos M.R. SantAnna, Carlos A. M. Fraga, Eliezer J. Barreiro

Ester Prodrugs of Ketoprofen: Synthesis, In Vitro Stability, In Vivo Biological Evaluation and In Silico Comparative Docking Studies Against COX-1 and COX-2

Journal: Current Drug Discovery Technologies
Volume: 13 Issue: 1 Year: 2016 Page: 41-57
Author(s): Musa Ahmed,Faizul Azam,Abdul Gbaj,Abdulmottaleb E. Zetrini,Amna S. Abodlal,Abir Rghigh,Eman Elmahdi,Amel Hamza,Mabruk Salama,Salah M. Bensaber

Research Article

Design, Synthesis and Biological Evaluation of New 1,3-diphenyl-3- (phenylamino)propan-1-ones as Selective Cyclooxygenase (COX-2) Inhibitors

Journal: Medicinal Chemistry
Volume: 14 Issue: 7 Year: 2018 Page: 652-659
Author(s): Shabnam Farzaneh,Soraya Shahhosseini,Hadi Arefi,Bahram Daraei,Marjan Esfahanizadeh,Afshin Zarghi

The Role of COX-1 and COX-2 in Alzheimers Disease Pathology and the Therapeutic Potentials of Non-Steroidal Anti-Inflammatory Drugs

Journal: Current Drug Targets - CNS & Neurological Disorders
Volume: 4 Issue: 3 Year: 2005 Page: 307-315
Author(s): Jeroen J.M. Hoozemans, M. Kerry OBanion

Chebulagic Acid Synergizes the Cytotoxicity of Doxorubicin in Human Hepatocellular Carcinoma Through COX-2 Dependant Modulation of MDR-1

Journal: Medicinal Chemistry
Volume: 7 Issue: 5 Year: 2011 Page: 432-442
Author(s): Chandrani Achari, Gorla V. Reddy, T. C.M. Reddy, Pallu Reddanna

The Interplay between Indoleamine 2,3-Dioxygenase 1 (IDO1) and Cyclooxygenase (COX)-2 In Chronic Inflammation and Cancer

Journal: Current Medicinal Chemistry
Volume: 18 Issue: 1 Year: 2011 Page: 2263-2271
Author(s): A. Cesario, B. Rocca, S. Rutella

Research Article

Virtual Screening, Molecular Docking, and Physiochemical Analysis ofNovel 1,3-diphenyl-2-propene-1-one as Dual COX-2/5-LOX Inhibitors

Journal: Letters in Drug Design & Discovery
Volume: 21 Issue: 2 Year: 2024 Page: 270-288
Author(s): Ajay Singh Kushwah

Structural and Electronic Factors Influencing the Selective Inhibition of COX-2

Journal: Mini-Reviews in Medicinal Chemistry
Volume: 16 Issue: 7 Year: 2016 Page: 579-594
Author(s): Fatma Aksakal,Natali Shvets,Veronika Khairullina,Anatholy Dimoglo

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