Search Result "CDK-2"


Research Article

Cordycepin Downregulates Cdk-2 to Interfere with Cell Cycle and Increases Apoptosis by Generating ROS in Cervical Cancer Cells: in vitro and in silico Study

Journal: Current Cancer Drug Targets
Volume: 19 Issue: 2 Year: 2019 Page: 152-159
Author(s): Mousumi Tania,Jakaria Shawon,Kazi Saif,Rudolf Kiefer,Mahdi Safaei Khorram,Mohammad A. Halim,Md. Asaduzzaman Khan

Research Article

Synthesis, Docking Studies into CDK-2 and Anticancer Activity of New Derivatives Based Pyrimidine Scaffold and Their Derived Glycosides

Journal: Mini-Reviews in Medicinal Chemistry
Volume: 19 Issue: 13 Year: 2019 Page: 1093-1110
Author(s): Adel A.H. Abdel Rahman,Ibrahim F. Nassar,Amira K.F. Shaban,Dina S. EL-Kady,Hanem M. Awad,Wael A. El Sayed

Research Article

Design, Synthesis and Anticancer Activity of New Thiazole-Tetrazole or Triazole Hybrid Glycosides Targeting CDK-2 via Structure-Based Virtual Screening

Journal: Mini-Reviews in Medicinal Chemistry
Volume: 19 Issue: 11 Year: 2019 Page: 933-948
Author(s): Asmaa F. Kassem,Eman M. H. Abbas,Dina S. El-Kady,Hanem M. Awad,Wael A. El-Sayed

Review Article

Understanding the Structural Basis for Inhibition of Cyclin-Dependent Kinases. New Pieces in the Molecular Puzzle

Journal: Current Drug Targets
Volume: 18 Issue: 9 Year: 2017 Page: 1104-1111
Author(s): Nayara M. Bernhardt Levin,Val Oliveira Pintro,Mauricio Boff de Avila,Bruna Boldrini de Mattos,Walter Filgueira De Azevedo Jr.

Review Article

Inhibitors of Cyclin-Dependent Kinase 1/2 for Anticancer Treatment

Journal: Medicinal Chemistry
Volume: 16 Issue: 3 Year: 2020 Page: 307-325
Author(s): Jiajia Mou,Danghui Chen,Yanru Deng

Simultaneous Interruption of Signal Transduction and Cell Cycle Regulatory Pathways: Implications for New Approaches to the Treatment of Childhood Leukemias

Journal: Current Drug Targets
Volume: 8 Issue: 6 Year: 2007 Page: 751-759
Author(s): Steven Grant, Paul Dent

CDK Inhibitors Induce Mitochondria-mediated Apoptosis Through the Activation of Polyamine Catabolic Pathway in LNCaP, DU145 and PC3 Prostate Cancer Cells

Journal: Current Pharmaceutical Design
Volume: 20 Issue: 2 Year: 2014 Page: 180-188
Author(s): Elif Damla Arisan, Pinar Obakan, Ajda Coker-Gurkan, Annarica Calcabrini, Enzo Agostinelli, Narcin Palavan Unsal

Research Article

Catalytic Self-condensation of 5-Hydroxymethylfurfural over Modified Heteropolyacid

Journal: Current Catalysis
Volume: 6 Issue: 3 Year: 2017 Page: 193-200
Author(s): Anil B. Gawade,Ganapati D. Yadav

Recent Advances in Cyclin-Dependent Kinase Inhibition. Purine-Based Derivatives as Anti-Cancer Agents. Roles and Perspectives for the Future

Journal: Current Topics in Medicinal Chemistry
Volume: 2 Issue: 9 Year: 2002 Page: 1037-1050
Author(s): Jean-luc Haesslein, Nathalie Jullian

Research Article

Synthesis, Assessment of Antineoplastic Activity, and Molecular Dockingof Novel 2-Thioxo-oxazolidin-4-one Derivatives

Journal: Medicinal Chemistry
Volume: 18 Issue: 9 Year: 2022 Page: 980-989
Author(s): Eduardo Augusto Vasconcelos de Freitas Ramalho,Douglas Carvalho Francisco Viana,Moacyr Jesus Barreto de Melo Rêgo,Marina Galdino da Rocha Pitta

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