Search Result "BACE-2"


Large Scale Refolding and Purification of the Catalytic Domain of Human BACE-2 Produced in E. coli

Journal: Protein & Peptide Letters
Volume: 16 Issue: 2 Year: 2009 Page: 121-131
Author(s): T. L. Emmons, A. M. Mildner, J. M. Lull, J. W. Leone, H. D. Fischer, R. L. Heinrikson, A. G. Tomasselli

2D QSAR Studies on Series of Human Beta-secretase (BACE-1) Inhibitors

Journal: Medicinal Chemistry
Volume: 10 Issue: 2 Year: 2014 Page: 162-173
Author(s): Daniela Santos Cruz, Marcelo Santos Castilho

Beta-Secretase: Structure, Function, and Evolution

Journal: CNS & Neurological Disorders - Drug Targets
Volume: 7 Issue: 3 Year: 2008 Page: 278-294
Author(s): Chitra Venugopal, Christina M. Demos, K. S. Jagannatha Rao, Miguel A. Pappolla, Kumar Sambamurti

Research Article

Understanding the Binding Mechanism of Antagonist (AZD3293) Against BACE-1: Molecular Insights into Alzheimer’s Drug Discovery

Journal: Letters in Drug Design & Discovery
Volume: 17 Issue: 7 Year: 2020 Page: 850-857
Author(s): Sphelele Sosibo,Daniel Gyamfi Amoako,Anou Moise Somboro,Darren Delai Sun,Jane Catherine Ngila,Hezekiel Kumalo

Memapsin 2 (Beta-Secretase) Inhibitor Drug, between Fantasy and Reality

Journal: Current Alzheimer Research
Volume: 4 Issue: 4 Year: 2007 Page: 418-422
Author(s): Arun K. Ghosh, Geoffrey Bilcer, Lin Hong, Gerald Koelsch, Jordan Tang

Research Article

Prediction of Anti-Diabetic Drugs as Dual Inhibitors Against Acetylcholinesterase and Beta-Secretase: A Neuroinformatics Study

Journal: CNS & Neurological Disorders - Drug Targets
Volume: 15 Issue: 10 Year: 2016 Page: 1216-1221
Author(s): Sibhghatulla Shaikh,Syed Mohd. Danish Rizvi,Tabinda Suhail,Shazi Shakil,Adel M. Abuzenadah,Rukhsar Anis,Deeba Naaz,Ashraf Dallol,Mohd. Haneef,Adnan Ahmad,Latafat Choudhary

Research Article

Multitarget Therapeutic Effect of Fasudil in APP/PS1transgenic Mice

Journal: CNS & Neurological Disorders - Drug Targets
Volume: 16 Issue: 2 Year: 2017 Page: 199-209
Author(s): Jie-Zhong Yu,Yan-Hua Li,Chun-Yun Liu,Qing Wang,Qing-Fang Gu,Hui-Qing Wang,Guang-Xian Zhang,Bao-Guo Xiao,Cun-Gen Ma

Emerging Therapeutic Targets in Regenerative Medicine for the Treatment of Diabetes Mellitus: A Patent Literature Review

Journal: Recent Patents on Regenerative Medicine
Volume: 3 Issue: 1 Year: 2013 Page: 56-62
Author(s): Anabel Alvarez Mercado, Nadia Cobo-Vuilleumier, Eduardo Suarez Martin, Benoit R. Gauthier

β-Secretase as a Therapeutic Target for Inhibitor Drugs

Journal: Current Medicinal Chemistry
Volume: 9 Issue: 1 Year: 2002 Page: 1135-1144
Author(s): Arun K. Ghosh, Lin Hong, Jordan Tang

Memapsin 2 (Beta-Secretase) Inhibitors: Drug Development

Journal: Current Alzheimer Research
Volume: 5 Issue: 2 Year: 2008 Page: 121-131
Author(s): Arun K. Ghosh, Nagaswamy Kumaragurubaran, Ling Hong, Gerald Koelsh, Jordan Tang

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