Search Result "Atom-Centred Fragments"


Targeting Cancer Using Fragment Based Drug Discovery

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 12 Issue: 1 Year: 2012 Page: 40-48
Author(s): Andrew P. Turnbull, Susan M. Boyd

Fragment-based Designing for the Generation of Novel Leads Against BACE1

Journal: Central Nervous System Agents in Medicinal Chemistry
Volume: 15 Issue: 1 Year: 2015 Page: 52-64
Author(s): Sucharita Das,Sandipan Chakraborty,Soumalee Basu

Fragment-Based Discovery of Inhibitors of Protein Kinase B

Journal: Current Topics in Medicinal Chemistry
Volume: 9 Issue: 1 Year: 2009 Page: 1705-1717
Author(s): Thomas G. Davies, Steven J. Woodhead, Ian Collins

Grouping of Coefficients for the Calculation of Inter-Molecular Similarity and Dissimilarity using 2D Fragment Bit-Strings

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 5 Issue: 2 Year: 2002 Page: 155-166
Author(s): J. D. Holliday, C-Y Hu, P. Willett

Opportunities Offered by Fragment-Based Drug Design in Antibiotic Development

Ebook: Frontiers in Anti-Infective Drug Discovery
Volume: 8 Year: 2020
Author(s): Sanjay Yapabandara,Lorna Wilkinson-White,Sandro Ataide,Ann H. Kwan
Doi: 10.2174/9789811412387120080005

NMR Screening and Hit Validation in Fragment Based Drug Discovery

Journal: Current Topics in Medicinal Chemistry
Volume: 11 Issue: 1 Year: 2011 Page: 43-67
Author(s): Ramon Campos-Olivas

Fragment Based Strategies for Discovery of Novel HIV-1 Reverse Transcriptase and Integrase Inhibitors

Journal: Current Topics in Medicinal Chemistry
Volume: 16 Issue: 1 Year: 2016 Page: 1135-1153
Author(s): Catherine F. Latham, Jennifer La, Ricky N. Tinetti, David K. Chalmers, Gilda Tachedjian

An Integrated Approach to Fragment-Based Lead Generation:Philosophy, Strategy and Case Studies from AstraZenecas Drug Discovery Programmes

Journal: Current Topics in Medicinal Chemistry
Volume: 7 Issue: 1 Year: 2007 Page: 1600-1629
Author(s): Jeffrey S. Albert, Niklas Blomberg, Alexander L. Breeze, Alastair J. H. Brown, Jeremy N. Burrows, Philip D. Edwards, Rutger H. A. Folmer, Stefan Geschwindner, Ed J. Griffen, Peter W. Kenny, Thorsten Nowak, Lise-Lotte Olsson, Hitesh Sanganee, Adam B. Shapiro

Identifying Structural Features Related to the Biological Activity of a Series of AT1 Antagonists from Fragment-based Drug Design

Journal: Protein & Peptide Letters
Volume: 21 Issue: 6 Year: 2014 Page: 542-549
Author(s): Danielle da C. Silva,Vinícius G. Maltarollo,Kathia M. Honorio

Research Article

Novel Inhibitors of DNA Repair Enzyme TDP1 Combining Monoterpenoid and Adamantane Fragments

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 19 Issue: 4 Year: 2019 Page: 463-472
Author(s): Evgenii S. Mozhaitsev,Alexandra L. Zakharenko,Evgeniy V. Suslov,Dina V. Korchagina,Olga D. Zakharova,Inna A. Vasil'eva,Arina A. Chepanova,Ellena Black,Jinal Patel,Raina Chand,Jóhannes Reynisson,Ivanhoe K.H. Leung,Konstantin P. Volcho,Nariman F. Salakhutdinov,Olga I. Lavrik

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