Search Result "3-phosphoinositide-dependent protein kinase-1 (PDK1)"


Targeting PDK1 in Cancer

Journal: Current Medicinal Chemistry
Volume: 18 Issue: 1 Year: 2011 Page: 2763-2769
Author(s): C. Raimondi, M. Falasca

Research Article

Investigation of Binding Characteristics of Phosphoinositide-dependent Kinase-1 (PDK1) Co-crystallized Ligands Through Virtual Pharmacophore Modeling Leading to Novel Anti-PDK1 Hits

Journal: Medicinal Chemistry
Volume: 16 Issue: 7 Year: 2020 Page: 860-880
Author(s): Iman A. Mansi,Mahmoud A. Al-Sha'er,Nizar M. Mhaidat,Mutasem O. Taha,Rand Shahin

A New Molecular Target of Insulin Action: Regulating the Pivotal PDK1

Journal: Current Drug Targets - Immune, Endocrine & Metabolic Disorders
Volume: 1 Issue: 3 Year: 2001 Page: 209-221
Author(s): K.L.R. Wick, F. Liu

PI3K/Akt/mTOR Pathway Inhibitors in Cancer: A Perspective on Clinical Progress

Journal: Current Medicinal Chemistry
Volume: 17 Issue: 3 Year: 2010 Page: 4326-4341
Author(s): P. Wu, Y.-Z. Hu

Efficient Identification of Novel Leads by Dynamic Focused Screening: PDK1 Case Study

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 13 Issue: 1 Year: 2010 Page: 16-26
Author(s): Dongyu Sun, Joon Jung, Thomas S. Rush III, Zangwei Xu, Michael J. Weber, Ekaterina Bobkova, Alan Northrup, Ilona Kariv

Selective Cyclooxygenase-2 Inhibitors for Malignant Glioma Therapy: Molecular Targets Beyond COX-2

Ebook: Advances in Anticancer Agents in Medicinal Chemistry
Volume: 1 Year: 2013
Author(s): Axel H. Schönthal
Doi: 10.2174/9781608054930113010011

Recent Progress in Signal Transduction Research of the Angiotensin II Type-1 Receptor: Protein Kinases, Vascular Dysfunction and Structural Requirement

Journal: Current Medicinal Chemistry - Cardiovascular & Hematological Agents
Volume: 3 Issue: 4 Year: 2005 Page: 305-322
Author(s): H. Suzuki, E. D. Motley, G. D. Frank, H. Utsunomiya, S. Eguchi

Regulation and Importance of the PI3K/Akt/mTOR Signaling Pathway in Hematologic Malignancies

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 9 Issue: 9 Year: 2009 Page: 1024-1038
Author(s): Kiyotaka Kawauchi, Toshie Ogasawara, Masako Yasuyama, Kuniaki Otsuka, Osamu Yamada

The PKB/AKT Pathway in Cancer

Journal: Current Pharmaceutical Design
Volume: 16 Issue: 1 Year: 2010 Page: 34-44
Author(s): Amancio Carnero

Protein Kinase C-Related Kinase (PKN/PRK). Potential Key-Role for PKN1 in Protection of Hypoxic Neurons

Journal: Current Neuropharmacology
Volume: 12 Issue: 3 Year: 2014 Page: 213-218
Author(s): Bettina Thauerer,Stephanie zur Nedden,Gabriele Baier-Bitterlich

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