Search Result "β-secretase inhibition"


Research Article

Berberine Alleviates Amyloid-Beta Pathology in the Brain of APP/PS1 Transgenic Mice via Inhibiting β/γ-Secretases Activity and Enhancing α-Secretases

Journal: Current Alzheimer Research
Volume: 15 Issue: 11 Year: 2018 Page: 1045-1052
Author(s): Zhiyou Cai,Chuanling Wang,Wenbo He,Yi Chen

Computer-Aided Drug Design Applied to Beta and Gamma Secretase Inhibitors-Perspectives for New Alzheimer Disease Therapy

Journal: Current Enzyme Inhibition
Volume: 2 Issue: 4 Year: 2006 Page: 311-328
Author(s): Speranta Avram, Adina L. Milac, Dan F. Mihailescu, Aurelia Dabu, Maria L. Flonta

Design of Some New Potent Beta-secretase Inhibitors Based on QSAR and Molecular Modeling Study on a Series of Hydroxyethylamine Derivatives

Journal: Letters in Drug Design & Discovery
Volume: 10 Issue: 3 Year: 2013 Page: 253-265
Author(s): YashShree Pandey,Satya Prakash Gupta

2D QSAR Studies on Series of Human Beta-secretase (BACE-1) Inhibitors

Journal: Medicinal Chemistry
Volume: 10 Issue: 2 Year: 2014 Page: 162-173
Author(s): Daniela Santos Cruz, Marcelo Santos Castilho

Memapsin 2 (Beta-Secretase) Inhibitors: Drug Development

Journal: Current Alzheimer Research
Volume: 5 Issue: 2 Year: 2008 Page: 121-131
Author(s): Arun K. Ghosh, Nagaswamy Kumaragurubaran, Ling Hong, Gerald Koelsh, Jordan Tang

Memapsin 2 (Beta-Secretase) Inhibitor Drug, between Fantasy and Reality

Journal: Current Alzheimer Research
Volume: 4 Issue: 4 Year: 2007 Page: 418-422
Author(s): Arun K. Ghosh, Geoffrey Bilcer, Lin Hong, Gerald Koelsch, Jordan Tang

Review Article

Role of γ-Secretase Inhibitors for the Treatment of Diverse Disease Conditions through Inhibition of Notch Signaling Pathway

Journal: Current Drug Targets
Volume: 22 Issue: 15 Year: 2021 Page: 1799-1807
Author(s): Arijit Mondal,Sankhadip Bose,Sabyasachi Banerjee,Dilipkumar Pal

Strategies to Diminish the Ab Load in Alzheimers Disease

Journal: Current Medicinal Chemistry - Central Nervous System Agents
Volume: 5 Issue: 1 Year: 2005 Page: 15-28
Author(s): A. C. Cuello, K. F.S. Bell

Inhibition of BACE, a Promising Approach to Alzheimers Disease Therapy

Journal: Current Topics in Medicinal Chemistry
Volume: 2 Issue: 4 Year: 2002 Page: 359-370
Author(s): Silvio Roggo

BACE1 Inhibitors: Attractive Therapeutics for Alzheimer’s Disease

Ebook: Drug Design and Discovery in Alzheimer's Disease
Volume: 1 Year: 2015
Author(s): Boris Decourt,MiMi Macias,Marwan Sabbagh,Abdu Adem
Doi: 10.1016/B978-0-12-803959-5.50010-6

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