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Research Article

3D-QSAR and Docking Studies on Pyrimidine Derivatives as CSF-1R Inhibitors

Journal: Letters in Drug Design & Discovery
Volume: 17 Issue: 3 Year: 2020 Page: 341-355
Author(s): Ya-ting Deng,Jun-wei Wang,Han Chu,Juan Wang,Yong Hu,Yong lin,Mao Shu,Zhi-hua Lin

Research Article

Evaluation of A Novel GLP-1R Ligand for PET Imaging of Prostate Cancer

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 19 Issue: 4 Year: 2019 Page: 509-514
Author(s): Yuanyuan Yue,Yuping Xu,Lirong Huang,Donghui Pan,Zhicheng Bai,Lizhen Wang,Runlin Yang,Junjie Yan,Huizhu Song,Xiaotian Li,Min Yang

Crosstalk between IGF-1R and other Tumor Promoting Pathways

Journal: Current Pharmaceutical Design
Volume: 20 Issue: 17 Year: 2014 Page: 2912-2921
Author(s): Changyu Liu,Zheng Zhang,Hexiao Tang,Zhixiao Jiang,Liangkun You,Yongde Liao

The Synergistic Effect of Humanized Monoclonal Antibodies Targeting Insulin-Like Growth Factor 1 Receptor (IGF-1R) and Chemotherapy

Journal: Current Drug Targets
Volume: 15 Issue: 7 Year: 2014 Page: 674-680
Author(s): Ping Sui, Hongxin Cao, Long Meng, Pingping Hu, Honghai Ma, Jiajun Du

Research Article

IGF-1R Inhibitor Ameliorates Diabetic Nephropathy with Suppressed HMGN1/TLR4 Pathway

Journal: Endocrine, Metabolic & Immune Disorders - Drug Targets
Volume: 18 Issue: 3 Year: 2018 Page: 241-250
Author(s): Jiali Yu,Jingjing Da,Rong Dong,Yi Sun,Yingjie Nie,Fuxun Yu,Li Zuo,Yan Zha

Review Article

Neurokinin-1 Receptor (NK-1R) Antagonists: Potential Targets in the Treatment of Glioblastoma Multiforme

Journal: Current Medicinal Chemistry
Volume: 28 Issue: 24 Year: 2021 Page: 4877-4892
Author(s): Amir R. Afshari,Ali Motamed-Sanaye,Hamed Sabri,Arash Soltani,Sepideh Karkon-Shayan,Sarvin Radvar,Hossein Javid,Hamid Mollazadeh,Thozhukat Sathyapalan,Amirhossein Sahebkar

Inhibiting the Interaction of cMET and IGF-1R with FAK Effectively Reduces Growth of Pancreatic Cancer Cells in vitro and in vivo

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 13 Issue: 4 Year: 2013 Page: 595-602
Author(s): Deniz A. Ucar, Andrew T. Magis, Di-Hua He, Nicholas J. Lawrence, Said M. Sebti, Elena Kurenova, Maria Zajac-Kaye, Jianliang Zhang, Steven N. Hochwald

A Novel Small Molecule Inhibitor of FAK and IGF-1R Protein Interactions Decreases Growth of Human Esophageal Carcinoma

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 11 Issue: 7 Year: 2011 Page: 629-637
Author(s): Deniz A. Ucar, Audrey Cox, Di-Hua He, David A. Ostrov, Elena Kurenova, Steven N. Hochwald

Insulin-like Growth Factor-1 Receptor (IGF-1R) Kinase Inhibitors in Cancer Therapy: Advances and Perspectives

Journal: Current Pharmaceutical Design
Volume: 18 Issue: 20 Year: 2012 Page: 2901-2913
Author(s): Mengzhu Xue,Xianwen Cao,Ye Zhong,Dong Kuang,Xiaofeng Liu,Zhenjiang Zhao,Honglin Li

SIGIRR / TIR8: A Negative Regulator of Toll-IL-1R Signaling

Journal: Current Medicinal Chemistry - Anti-Inflammatory & Anti-Allergy Agents
Volume: 4 Issue: 1 Year: 2005 Page: 21-27
Author(s): Xiaoxia Li, Jinzhong Qin

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