Search Result "α-secretase-derived fragments"


Fragment-Based Drug Design: Computational and Experimental State of the Art

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 14 Issue: 6 Year: 2011 Page: 500-520
Author(s): Laurent Hoffer, Jean-Paul Renaud, Dragos Horvath

Review Article

Proteolytic Cleavage of Polyglutamine Disease-Causing Proteins: Revisiting the Toxic Fragment Hypothesis

Journal: Current Pharmaceutical Design
Volume: 23 Issue: 5 Year: 2017 Page: 753-775
Author(s): Carlos A. Matos,Luis Pereira de Almeida,Clevio Nobrega

Targeted Hydrolysis of Beta-Amyloid with Engineered Antibody Fragments

Journal: Current Alzheimer Research
Volume: 7 Issue: 3 Year: 2010 Page: 214-222
Author(s): S. Kasturirangan, M. Sierks

NMR Screening and Hit Validation in Fragment Based Drug Discovery

Journal: Current Topics in Medicinal Chemistry
Volume: 11 Issue: 1 Year: 2011 Page: 43-67
Author(s): Ramon Campos-Olivas

Role of Ligand-Based Drug Design Methodologies toward the Discovery of New Anti- Alzheimer Agents: Futures Perspectives in Fragment-Based Ligand Design

Journal: Current Medicinal Chemistry
Volume: 19 Issue: 11 Year: 2012 Page: 1635-1645
Author(s): A. Speck-Planche,F. Luan,M. N.D.S. Cordeiro

Tumor-Derived Extracellular Fragments of Receptor Protein Tyrosine Phosphatases (RPTPs) as Cancer Molecular Diagnostic Tools

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 11 Issue: 1 Year: 2011 Page: 133-140
Author(s): Sonya E.L. Craig, Susann M. Brady-Kalnay

The ATP-Binding Cassette Transporter-2 (ABCA2) Increases Endogenous Amyloid Precursor Protein Expression and Abeta Fragment Generation

Journal: Current Alzheimer Research
Volume: 7 Issue: 7 Year: 2010 Page: 566-577
Author(s): W. Davis

Diverse Functions of ? -secretase: Releasing Signaling Fragments and Deleterious Molecules

Journal: Current Enzyme Inhibition
Volume: 9 Issue: 1 Year: 2013 Page: 15-27
Author(s): Sun-Ho Han, Chaeyoung Kim, Inhee Mook-Jung

Cellular Prion and its Catabolites in the Brain: Production and Function

Journal: Current Molecular Medicine
Volume: 12 Issue: 3 Year: 2012 Page: 304-315
Author(s): M.-V. Guillot-Sestier, F. Checler

Research Article

Rescue of Hypovitaminosis A Induces Non-Amyloidogenic Amyloid Precursor Protein (APP) Processing

Journal: Current Alzheimer Research
Volume: 13 Issue: 11 Year: 2016 Page: 1277-1289
Author(s): Sven Reinhardt,Marcus O.W. Grimm,Christoph Stahlmann,Tobias Hartmann,Koichi Shudo,Taisuke Tomita,Kristina Endres

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