Abstract
Using a methodology based on HPLC fractionation, mass spectrometry analysis, and microinjection guide-bioassays, a peptide with toxicity to both insects and mammals was isolated from the venom of the scorpion Leiurus quinquestriatus hebraeus, and named LqhIV (after LqhII and LqhIII[1]). The primary sequence, circular dichroism spectrum and three-dimensional structure simulation of LqhIV indicate that it contains similar structure to that of the group of alpha scorpion toxins.
Keywords: Leiurus quinquestriatus hebraeus, Androctonus australis, Leiurus quinquestriatus quinquestriatus, Hebraeus, Quinquestriatus
Protein & Peptide Letters
Title: Isolation and Structural Characterization of a Peptide from the Venom of Scorpion with Toxicity Towards Invertebrates and Vertebrates
Volume: 8 Issue: 5
Author(s): Gerardo Corzo, Elba Villegas and Terumi Nakajima
Affiliation:
Keywords: Leiurus quinquestriatus hebraeus, Androctonus australis, Leiurus quinquestriatus quinquestriatus, Hebraeus, Quinquestriatus
Abstract: Using a methodology based on HPLC fractionation, mass spectrometry analysis, and microinjection guide-bioassays, a peptide with toxicity to both insects and mammals was isolated from the venom of the scorpion Leiurus quinquestriatus hebraeus, and named LqhIV (after LqhII and LqhIII[1]). The primary sequence, circular dichroism spectrum and three-dimensional structure simulation of LqhIV indicate that it contains similar structure to that of the group of alpha scorpion toxins.
Export Options
About this article
Cite this article as:
Corzo Gerardo, Villegas Elba and Nakajima Terumi, Isolation and Structural Characterization of a Peptide from the Venom of Scorpion with Toxicity Towards Invertebrates and Vertebrates, Protein & Peptide Letters 2001; 8 (5) . https://dx.doi.org/10.2174/0929866013409256
DOI https://dx.doi.org/10.2174/0929866013409256 |
Print ISSN 0929-8665 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5305 |

- Author Guidelines
- Bentham Author Support Services (BASS)
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Recent Patents on Drugs Addressing Neurodegenerative Diseases
Recent Patents on Biomarkers Moving Pictures: Imaging Flow Cytometry for Drug Development
Combinatorial Chemistry & High Throughput Screening Meet Our Editorial Board Member
Endocrine, Metabolic & Immune Disorders - Drug Targets Sepsis: Links between Pathogen Sensing and Organ Damage
Current Pharmaceutical Design Myopericarditis, as the First Sign of Rheumatoid Arthritis Relapse, Evaluated by Cardiac Magnetic Resonance
Inflammation & Allergy - Drug Targets (Discontinued) Associations of Body Mass Index and Obesity-Related Genetic Variants with Serum Metabolites
Current Metabolomics Transition of Growth Hormone Treatment: Adolescence to Adulthood
Current Pediatric Reviews C7-Substituted Estranes and Related Steroids
Mini-Reviews in Organic Chemistry A Role for Leptin in the Systemic Inflammatory Response Syndrome (SIRS) and in Immune Response, an Update
Current Medicinal Chemistry A Brief Overview of Tyrosine Hydroxylase and α-Synuclein in the Parkinsonian Brain
CNS & Neurological Disorders - Drug Targets Intravitreal Injections and Diabetic Macular Edema: Actual and New Therapeutic Options
Current Diabetes Reviews Availability of Oral Formulations Labeled for Use in Young Children in Serbia, Germany and the USA
Current Pharmaceutical Design Statins and Vulnerable Plaque
Current Pharmaceutical Design Application of Carbon Monoxide for Transplantation
Current Pharmaceutical Biotechnology Local Drug Delivery Based Treatment Approaches for Effective Management of Periodontitis
Current Drug Therapy Thrombin-Activatable Fibrinolysis Inhibitor
Current Medicinal Chemistry Glaucoma Pathogenesis and Neurotrophins: Focus on the Molecular and Genetic Basis for Therapeutic Prospects
Current Neuropharmacology TRAIL-Based Therapeutic Approaches for the Treatment of Pediatric Malignancies
Current Medicinal Chemistry Targeting ADAM17 Sheddase Activity in Cancer
Current Drug Targets Molecular and Cellular Activities of Vitamin E Analogues
Mini-Reviews in Medicinal Chemistry